Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The measurement of oxidative stress status by fluorescence detection of spin-trapped adducts with reactive nitrogen and oxygen species

2016/23/D/ST4/01576

Keywords:

oxidative stress reactive nitrogen and oxygen species spin traps fluorescence spectroscopy high performance liquid chromatography coupled with mass spectrometry

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_6: Instrumental methods in chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Gdański, Wydział Chemii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Krzysztof Żamojć 

Number of co-investigators in the project: 3

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 633 085 PLN

Project start date (Y-m-d): 2017-07-13

Project end date (Y-m-d): 2022-07-12

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wysokosprawny chromatograf cieczowy (HPLC) z detektorem UV-DAD i fluorescencyjnym (np. Dionex Ultimate 3000 LC System) (251 600 PLN)

Information in the final report

  • Publication in academic press/journals (12)
  • Articles in post-conference publications (3)
  1. Fluorescence quenching studies on the interactions between chosen fluoroquinolones and selected stable TEMPO and PROXYL nitroxides
    Authors:
    Krzysztof Żamojć, Irena Bylińska, Wiesław Wiczk, Lech Chmurzyński
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: Article number: 885), Wydawca: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/ijms22020885 - link to the publication
  2. Key role of histidine residues orientation in affinity binding of model pentapeptides with Ni2+ ions: A theoretical supported experimental study
    Authors:
    Krzysztof Żamojć, Dariusz Wyrzykowski, Giuseppina Sabatino, Anna Maria Papini, Robert Wieczorek, Lech Chmurzyński, Joanna Makowska
    Academic press:
    Journal of Molecular Liquids (rok: 2021, tom: 341, strony: 117414), Wydawca: ELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.molliq.2021.117414 - link to the publication
  3. Physicochemical nature of sodium dodecyl sulfate interactions with bovine serum albumin revealed by interdisciplinary approaches
    Authors:
    Aleksandra Tesmar, Małgorzata M. Kogut, Krzysztof Żamojć, Ola Grabowska, Katarzyna Chmur, Sergey A. Samsonov, Joanna Makowska, Dariusz Wyrzykowski, Lech Chmurzyński
    Academic press:
    Journal of Molecular Liquids (rok: 2021, tom: 340, strony: 117185), Wydawca: ELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.molliq.2021.117185 - link to the publication
  4. Interactions of Aβ1-42 peptide and its three fragments (Aβ8-12, Aβ8-13, and Aβ5-16) with selected nonsteroidal drugs and compounds of natural origin
    Authors:
    Krzysztof Żamojć, Karolina Streńska, Dariusz Wyrzykowski, Lech Chmurzyński, Joanna Makowska
    Academic press:
    Symmetry (rok: 2020, tom: 12, strony: Article number: 1579), Wydawca: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/sym12101579 - link to the publication
  5. A pentapeptide with tyrosine moiety as fluorescent chemosensor for selective nanomolar-level detection of copper(II) ions
    Authors:
    Krzysztof Żamojć, Dominik Kamrowski, Magdalena Zdrowowicz, Dariusz Wyrzykowski, Wiesław Wiczk, Lech Chmurzyński, Joanna Makowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 20, strony: Article number: 743), Wydawca: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/ijms21030743 - link to the publication
  6. Dihydroxy-substituted coumarins as fluorescent probes for nanomolar-level detectionk of the 4-amino-TEMPO spin label
    Authors:
    Krzysztof Żamojć, Magdalena Zdrowowicz, Aleksandra Hać, Maciej Witwicki, Paweł Rudnicki-Velasquez, Dariusz Wyrzykowski, Wiesław Wiczk, Lech Chmurzyński
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: Article number: 3802), Wydawca: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/ijms20153802 - link to the publication
  7. Effect of tetraphenylborate on physicochemical properties of bovine serum albumin
    Authors:
    Ola Grabowska, Małgorzata M. Kogut, Krzysztof Żamojć, Sergey A. Samsonov, Joanna Makowska, Aleksandra Tesmar, Katarzyna Chmur, Dariusz Wyrzykowski, Lech Chmurzyński
    Academic press:
    Molecules (rok: 2021, tom: 26, strony: 6565), Wydawca: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
  8. On the effect of pH, temperature, and surfactant structure on bovine serum albumin–cationic/anionic/nonionic surfactants interactions in cacodylate buffer – fluorescence quenching studies supported by UV spectrophotometry and CD spectroscopy
    Authors:
    Krzysztof Żamojć, Dariusz Wyrzykowski, Lech Chmurzyński
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 41), Wydawca: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/ijms23010041 - link to the publication
  9. Tautomerism of N-substituted acridin-9-amines in the context of dynamic NMR and matrix isolation-FT-IR spectroscopy supported by DFT calculations and structural analysis
    Authors:
    Karol Krzymiński, Beata Zadykowicz, Piotr Storoniak, Michał Wera, Krzysztof Żamojć
    Academic press:
    Journal of Molecular Structure (rok: 2020, tom: 1218, strony: Article number: 128424), Wydawca: ELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2020.128424 - link to the publication
  10. Copper(II) complexation by fragment of central part of FBP28 protein from Mus musculus
    Authors:
    Joanna Makowska, Krzysztof Żamojć, Dariusz Wyrzykowski, Wiesław Wiczk, Lech Chmurzyński
    Academic press:
    Biophysical Chemistry (rok: 2018, tom: 241, strony: 55-60), Wydawca: ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.bpc.2018.08.002 - link to the publication
  11. On the use of acridinium indicators for the chemiluminecent determination of the total antioxidant capacity of dietary supplements
    Authors:
    Karol Krzymiński, Alexander Roshal, Paweł Rudnicki-Velasquez, Krzysztof Żamojć
    Academic press:
    Luminescence (rok: 2019, tom: 34, strony: 512-519), Wydawca: WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
    Status:
    Published
    DOI:
    10.1002/bio.3629 - link to the publication
  12. The influence of the type of substituents and the solvent on the interactions between different coumarins and selected TEMPO analogues – Fluorescence quenching studies
    Authors:
    Krzysztof Żamojć, Wiesław Wiczk, Lech Chmurzyński
    Academic press:
    Chemical Physics (rok: 2018, tom: 513, strony: 188-194), Wydawca: ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.chemphys.2018.08.005 - link to the publication
  1. Badania aktywności przeciwutleniającej związków kompleksowych oksowanadu(IV)
    Authors:
    Aleksandra Tesmar, Dariusz Wyrzykowski, Krzysztof Żamojć, Joanna Makowska, Lech Chmurzyński
    Conference:
    XI Ogólnopolskie Sympozjum "Nauka i przemysł - metody spektroskopowe w praktyce, nowe wyzwania i możliwości" (rok: 2019, ), Wydawca: Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, Lublin
    Data:
    konferencja 25-27 czerwca 2019 r.
    Status:
    Published
  2. Wykorzystanie pułapek spinowych w oznaczaniu wolnych rodników
    Authors:
    Krzysztof Żamojć, Joanna Makowska, Dariusz Wyrzykowski, Lech Chmurzyński
    Conference:
    XI Ogólnopolskie Sympozjum "Nauka i przemysł - metody spektroskopowe w praktyce, nowe wyzwania i możliwości" (rok: 2019, ), Wydawca: Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, Lublin
    Data:
    konferencja 25-27 czerwca 2019 r.
    Status:
    Published
  3. Wykorzystanie metody kalorymetrycznej oraz spektroskopii fluorescencyjnej do badania oddziaływań fragmentu białka AB(1-42) z jonami miedzi(II)
    Authors:
    Joanna Makowska, Krzysztof Żamojć, Dariusz Wyrzykowski, Wiesław Wiczk, Lech Chmurzyński
    Conference:
    XI Ogólnopolskie Sympozjum "Nauka i przemysł - metody spektroskopowe w praktyce, nowe wyzwania i możliwości" (rok: 2019, ), Wydawca: Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, Lublin
    Data:
    konferencja 25-27 czerwca 2019 r.
    Status:
    Published