Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Role of MCPIP1 protein in epidermis physiology and pathophysiology.

2016/23/B/NZ3/00792

Keywords:

MCPIP1 RNase epidermis skin diseases

Descriptors:

  • NZ3_1: Cell biology
  • NZ5_3: Pathogenesis of human diseases
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jolanta Jura 

Number of co-investigators in the project: 5

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 055 060 PLN

Project start date (Y-m-d): 2017-07-20

Project end date (Y-m-d): 2021-07-19

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. 96-dołkowy termocykler do analizy PCR w czasie rzeczywistym (100 000 PLN)
  2. zamrażarka niskotemperaturowa (-80˚) (50 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Activity of MCPIP1 RNase in tumor associated processes
    Authors:
    Miekus K, Kotlinowski J, Lichawska-Cieslar A, Rys J, Jura J.
    Academic press:
    Journal of Experimental & Clinical Cancer Research (rok: 2019, tom: 38, strony: 45302), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s13046-019-1430-6 - link to the publication
  2. Loss of epidermal MCPIP1 is associated with aggressive squamous cell carcinoma
    Authors:
    Szukala W, Lichawska-Cieslar A, Pietrzycka R, Kulecka M, Rumienczyk I, Mikula M, Chlebicka I, Konieczny P, Dziedzic K, Szepietowski J C, Fontemaggi G, Rys J, Jura J.
    Academic press:
    Journal of Experimental & Clinical Cancer Research (rok: 2021, tom: 40:391, strony: 45305), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s13046-021-02202-3 - link to the publication
  3. Loss of keratinocyte Mcpip1 abruptly activates the IL-23/Th17 and Stat3 pathways in skin inflammation
    Authors:
    Lichawska-Cieslar A, Konieczny P, Szukala W, Declercq W, Fu M, Jura J.
    Academic press:
    Biochimica et Biophysica Acta - Molecular Cell Research (rok: 2021, tom: 1868 (1), strony: 45295), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2020.118866 - link to the publication
  4. MCPIP1 RNase and its multifaceted role
    Authors:
    Musson R, Szukała W, Jura J.
    Academic press:
    International Journal of Molecular Science (rok: 2020, tom: 21 (19), strony: 45305), Wydawca: MDPI Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ijms21197183 - link to the publication
  5. Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation
    Authors:
    Konieczny P, Lichawska-Cieslar A, Kwiecinska P, Cichy J, Pietrzycka R, Szukala W, Declercq W, Devos M, Paziewska A, Rumienczyk I, Kulecka M, Mikula M, Fu M, Borowczyk J, Santamaria-Babí LF, Jura J.
    Academic press:
    Journal of Molecular Medicine (rok: 2019, tom: 97 (12), strony: 1669-1684), Wydawca: Springer Science+Business Media
    Status:
    Published
    DOI:
    10.1007/s00109-019-01853-2 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy