Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of SWI/SNF chromatin remodelling complex in the epithelial-mesenchymal transition. Identification of interactions with SNAIL family transcription factors.

2016/23/N/NZ1/01138

Keywords:

SWI/SNF EMT cancer

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Iga Jancewicz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 149 200 PLN

Project start date (Y-m-d): 2017-07-18

Project end date (Y-m-d): 2020-07-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. wytrząsarka typu worteks (1 000 PLN)
  2. komputer (4 000 PLN)
  3. mieszadło magnetyczne z podgrzewaniem (2 000 PLN)
  4. pipeta elektroniczna (3 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. RRM2 gene expression depends on BAF180 subunit of SWISNF chromatin remodeling complex and correlates with abundance of tumor infiltrating lymphocytes in ccRCC
    Authors:
    Szarkowska Joanna, Cwiek Pawel, Szymanski Michal, Rusetska Natalia, Jancewicz Iga, Stachowiak Malgorzata, Swiatek Monika, Luba Maciej, Konopinski Ryszard, Kubala Szymon, Zub Renata, Jakub Kucharz, Wiechno Pawel, Siedlecki Janusz A., Markowicz Sergiusz, Sarnowska Elzbieta1, Sarnowski Tomasz J.
    Academic press:
    American Journal of Cancer Research , Wydawca: e-Century Publishing Corporation
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  2. BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling complex—a tumour suppressor or tumour-promoting factor?
    Authors:
    Jancewicz Iga, Siedlecki Janusz A., Sarnowski Tomasz J., Sarnowska Elżbieta
    Academic press:
    Epigenetics & Chromatin (rok: 2019, tom: 12, strony: -), Wydawca: BMC
    Status:
    Published
    DOI:
    10.1186/s13072-019-0315-4 - link to the publication
  3. PD-L1 Overexpression, SWI/SNF Complex Deregulation, and Profound Transcriptomic Changes Characterize Cancer-Dependent Exhaustion of Persistently Activated CD4+ T Cells
    Authors:
    Iga Jancewicz, Joanna Szarkowska, Ryszard Konopinski, Malgorzata Stachowiak, Monika Swiatek, Katarzyna Blachnio, Szymon Kubala, Paulina Oksinska, Pawel Cwiek, Natalia Rusetska, Agnieszka Tupalska, Natalia Zeber-Lubecka, Ewa Grabowska, Bianka Swiderska, Agata Malinowska, Michal Mikula, Beata Jagielska, Jan Walewski, Janusz A. Siedlecki, Tomasz J. Sarnowski, Sergiusz Markowicz, Elzbieta A. Sarnowska
    Academic press:
    Cancers (Basel) (rok: 2021, tom: 13(16), strony: 4148), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13164148 - link to the publication
  1. The role of SWI/SNF chromatin remodelling complex ATPase subunit - BRM in TNBC
    Authors:
    I Jancewicz N Rusetska A Armatowska M Stachowiak K Pogoda A Niwińska W Olszewski Z I Nowecki T J Sarnowski E Sarnowska J A Siedlecki
    Conference:
    ESMO 2018 (rok: 2018, ), Wydawca: Annals of Oncology
    Data:
    konferencja 19-23 października 2018
    Status:
    Published

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