Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Conformational epitopes of canine leukocyte antigens DR (DLA-DR) as targets diagnosis and experimental therapy of lymphoma

2016/21/N/NZ5/01942

Keywords:

lymphoma DLA-DR dog monoclonal antibodies MHC II

Descriptors:

  • NZ5_6: Diagnostics in animal diseases
  • NZ5_8: Animal disease treatment

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Marta Lisowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2017-01-27

Project end date (Y-m-d): 2020-01-26

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Laminar komórkowy klasy II bezpieczeństwa biologicznego (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. An antibody specific to dog leukocyte antigen DR (DLA-DR) and its novel methotrexate conjugate inhibit the growth of canine B cell lymphoma
    Authors:
    Lisowska M, Milczarek M, Ciekot J, Kutkowska J, Rapak A, Miazek A
    Academic press:
    Cancers (rok: 2019, tom: 11, strony: 1438), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers11101438 - link to the publication
  2. Development of novel monoclonal antibodies to dog leukocyte antigen DR (DLA-DR) displaying direct and immune-mediated cytotoxicity towards lymphoma cell lines
    Authors:
    Marta Lisowska, Aleksandra Pawlak, Justyna Kutkowska, Wojciech Hildebrand, Maciej Ugorski, Andrzej Rapak, Arkadiusz Miazek
    Academic press:
    Hematological Oncology (rok: 2018, tom: 36, strony: 554-560), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/hon.2507 - link to the publication

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