Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Identification and characterization of proteins with link topology

2016/21/N/NZ1/02848

Keywords:

proteins topology links knots simulations

Descriptors:

  • NZ1_3: Biophysics
  • NZ1_4: Structural biology
  • ST1_6: Topology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Paweł Dąbrowski-Tumański 

Number of co-investigators in the project: 3

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2017-01-24

Project end date (Y-m-d): 2019-10-23

Project duration:: 33 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Serwer obliczeniowy (22 000 PLN)

Information in the final report

  • Publication in academic press/journals (9)
  1. KnotProt 2.0: a database of proteins with knots and other entangled structures
    Authors:
    Dabrowski-Tumanski P, Rubach P, Goundaroulis D, Dorier J, Sułkowski P, Millett KC, Rawdon EJ, Stasiak A, Sulkowska JI
    Academic press:
    Nucleic Acids Research (rok: 2018, tom: 47, strony: D367-D375), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gky1140 - link to the publication
  2. The exclusive effects of chaperonin on the behavior of proteins with 52 knot
    Authors:
    Zhao Y, Dabrowski-Tumanski P, Niewieczerzal S, Sulkowska JI
    Academic press:
    PLoS Computational Biology (rok: 2018, tom: 14, strony: e1005970), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pcbi.1005970 - link to the publication
  3. PyLasso: a PyMOL plugin to identify lassos
    Authors:
    Aleksandra M Gierut, Wanda Niemyska, Pawel Dabrowski-Tumanski, Piotr Sułkowski, Joanna I Sulkowska
    Academic press:
    Bioinformatics (rok: 2017, tom: 33, strony: 3819–3821), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/bioinformatics/btx493 - link to the publication
  4. To Tie or Not to Tie? That Is the Question
    Authors:
    Pawel Dabrowski-Tumanski, Joanna I. Sulkowska
    Academic press:
    Polymers (rok: 2017, tom: 9, strony: 454), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/polym9090454 - link to the publication
  5. GapRepairer–a server to model a structural gap and validate it using topological analysis
    Authors:
    Jarmolinska AI, Kadlof M, Dabrowski-Tumanski P, Sulkowska JI
    Academic press:
    Bioinformatics (rok: 2018, tom: 34, strony: 3300-3307), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/bioinformatics/bty334 - link to the publication
  6. Protein Knotting by Active Threading of Nascent Polypeptide Chain Exiting From the Ribosome Exit Channel
    Authors:
    Dabrowski-Tumanski P, Piejko M, Niewieczerzal S, Stasiak A, Sulkowska JI
    Academic press:
    Journal of Physical Chemistry B (rok: 2018, tom: 122, strony: 11616-11625), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.8b07634 - link to the publication
  7. PyLink: a PyMOL plugin to identify links
    Authors:
    Gierut A, Dabrowski-Tumanski P, Niemyska W, Millett KC, Sulkowska JI
    Academic press:
    Bioinformatics (rok: 2019, tom: bty1038, strony: bty1038), Wydawca: Oxford University Press}
    Status:
    Published
    DOI:
    10.1093/bioinformatics/bty1038 - link to the publication
  8. Statistical Properties of Lasso-Shape Polymers and Their Implications for Complex Lasso Proteins Function
    Authors:
    Pawel, Dabrowski-Tumanski, Bartosz Gren, Joanna I Sulkowska
    Academic press:
    Polymers (rok: 2019, tom: 11, strony: 707), Wydawca: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/polym11040707 - link to the publication
  9. Genus trace reveals the topological complexity and domain structure of biomolecules
    Authors:
    Zajac S, Geary C, Andersen ES, Dabrowski-Tumanski P, Sulkowska JI, Sułkowski P
    Academic press:
    Scientific Reports (rok: 2018, tom: 8, strony: 17537), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-018-35557-3 - link to the publication