Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The vulnerable coronary plaque burden associated with impaired healing potential of plasma fibrin network determines persistent prothrombotic hazard after myocardial infarction.

2016/21/B/NZ5/01378

Keywords:

intracoronary thrombus unstable atherosclerotic plaque myocardial infarction fibrin network

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński-Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Jarosław Zalewski 

Number of co-investigators in the project: 3

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 1 385 380 PLN

Project start date (Y-m-d): 2017-02-09

Project end date (Y-m-d): 2022-11-08

Project duration:: 69 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer z monitorem (10 000 PLN)
  2. Oprogramowanie do analizy statystycznej i analizy obrazów (5 000 PLN)
  3. Wirówka laboratoryjna (15 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. Polyhedral erythrocytes in intracoronary thrombus and their association with reperfusion in myocardial infarction.
    Authors:
    Zalewski J, Lewicki L, Krawczyk K, Zabczyk M, Targonski R, Molek P, Nessler J, Undas A
    Academic press:
    Clinical Research in Cardiology (rok: 2019, tom: 2019 Feb 1., strony: ahead of print), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00392-019-01425-x - link to the publication
  2. Coronary artery dissection following aortic valve replacement. How can one deal with this rare yet life-threatening complication?
    Authors:
    Molek P, Nessler J, Zalewski J
    Academic press:
    Journal of Cardiac Surgery (rok: 2019, tom: 34 (3), strony: 147-150), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/jocs. - link to the publication
  3. The shifted balance of arginine metabolites in acute myocardial infarction patients and its clinical relevance
    Authors:
    Molek P, Zmudzki P, Wlodarczyk A, Nessler J, Zalewski J
    Academic press:
    Scientific Reports (rok: 2021, tom: 11, strony: 83), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-80230-3 - link to the publication
  4. Thin-cap fibroatheroma and increased coronary intima-media thickness are associated with an altered arginine metabolites balance
    Authors:
    Mołek P, Żmudzki P, Machnik A, Nowak G, Stępień K, Wnuk M, Włodarczyk A, Nowak K, Rychlak R, Nessler J, Zalewski J
    Academic press:
    Polisch Archives of Internal Medicine (rok: 2022, tom: ahead of print, strony: ahead of print), Wydawca: Viamedica
    Status:
    Published
    DOI:
    10.20452/pamw.16356 - link to the publication
  5. Worse long‑term prognosis in myocardial infarction occurring at weekends or public holidays with insight into myocardial infarction with nonobstructive coronary arteries
    Authors:
    Stępień K, Nowak K, Nessler J, Zalewski J
    Academic press:
    Polish Archives of Internal Medicine (rok: 2020, tom: 130, strony: 942-950), Wydawca: Medycyna Praktyczna
    Status:
    Published
    DOI:
    10.20452/pamw.15615 - link to the publication
  6. Complicating acute myocardial infarction. Current status and unresolved targets for subsequent research.
    Authors:
    Zalewski J, Nowak K, Furczynska P, Zalewska M
    Academic press:
    Journal of Clinical Medicine (rok: 2021, tom: 10, strony: 5904), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm10245904 - link to the publication

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