Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Elaboration and characteristics of biocomposites with anti-virulent and anti-bacterial properties against Pseudomonas aeruginosa

2016/21/B/NZ6/01157

Keywords:

Pseudomonas aeruginosa biofilm phage virulence biocomposite

Descriptors:

  • NZ6_4: Bacteriology
  • NZ6_5: Virology
  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Zuzanna Drulis-Kawa 

Number of co-investigators in the project: 11

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 1 480 600 PLN

Project start date (Y-m-d): 2017-05-19

Project end date (Y-m-d): 2022-05-18

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. zestaw dwóch kuwet kwarcowych pozwalających na ocenę dyfuzji w insertach z zastosowaniem techniki interferometrii laserowej z układem stabilizującym temperaturę (50 000 PLN)
  2. czytnik mikropłytek VARIOSKAN LUX THERMO (140 000 PLN)
  3. zestaw laserów i MCOMB.
  4. System do Real-Time qPCR typu CFX96 Touch System (150 000 PLN)
  5. kamera ORCA-Flasch CMOS do mikroskopu konfokalnego (150 000 PLN)

Information in the final report

  • Publication in academic press/journals (18)
  • Articles in post-conference publications (1)
  1. A Study of the Impact of Graphene Oxide on Viral Infection Related to A549 and TC28a2 Human Cell Lines
    Authors:
    Piotr Kuropka, Maciej Dobrzynski, Barbara Bazanow, Dominika Stygar, Tomasz Gebarowski, Anna Leskow, Malgorzata Tarnowska, Katarzyna Szyszka, Malgorzata Malecka, Nicole Nowak, Wieslaw Strek, Rafal J.Wiglusz
    Academic press:
    Materials (rok: 2021, tom: 14, strony: 7788), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  2. Editorial Special Issue: Bacteriophages and Biofilms"
    Authors:
    Zuzanna Drulis-Kawa, Barbara Maciejewska
    Academic press:
    Viruses (rok: 2021, tom: 13, strony: 257), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v13020257 - link to the publication
  3. Applications of bacteriophages versus phage enzymes to combat and cure bacterial infections: an ambitious and also a realistic application?
    Authors:
    Barbara Maciejewska, Tomasz Olszak, Zuzanna Drulis-Kawa
    Academic press:
    Applied Microbiology and Biotechnology (rok: 2018, tom: 102, strony: 2563–2581), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00253-018-8811-1 - link to the publication
  4. New Approach to Antifungal Activity of Fluconazole Incorporated into the Porous 6-Anhydro--L-Galacto--D -Galactan Structures Modified with Nanohydroxyapatite for Chronic-Wound Treatments—In Vitro Evaluation
    Authors:
    Justyna Rewak-Soroczynska, Paulina Sobierajska, Sara Targonska, Agata Piecuch, Lukasz Grosman, Jaroslaw Rachuna, SlawomirWasik, Michal Arabski, Rafal Ogorek and Rafal J. Wiglusz
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 3112), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22063112 - link to the publication
  5. Preparation of a New Biocomposite Designed for Cartilage Grafting with Antibiofilm Activity
    Authors:
    Sara Targonska, Justyna Rewak-Soroczynska, Agata Piecuch, Emil Paluch, Damian Szymanski, and Rafal J. Wiglusz
    Academic press:
    ACS Omega (rok: 2020, tom: 38, strony: 5, 38, 24546–24557), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acsomega.0c03044 - link to the publication
  6. Targeting biofilms using phages and their enzymes
    Authors:
    Joana Azeredo, Pilar Garcıa, Zuzanna Drulis-Kawa
    Academic press:
    Current Opinion in Biotechnology (rok: 2021, tom: 68, strony: 251–261), Wydawca: Elsevier Ltd.
    Status:
    Published
    DOI:
    10.1016/j.c - link to the publication
  7. The In Vitro Anti-Pseudomonal Activity of Cu2+, Strawberry Furanone, Gentamicin, and Lytic Phages Alone and in Combination: Pros and Cons
    Authors:
    Agata Dorotkiewicz-Jach, Pawel Markwitz, Zuzanna Drulis-Kawa
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 11562), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22189830 - link to the publication
  8. The impact of agarose immobilization on the activity of lytic Pseudomonas aeruginosa phages combined with chemicals
    Authors:
    Agata Dorotkiewicz-Jach; Pawel Markwitz; Jarosław Rachuna; Michał Arabski; Zuzanna Drulis-Kawa
    Academic press:
    Applied Microbiology and Biotechnology , Wydawca: Springer
    Status:
    Submitted
    DOI:
    brak - link to the publication
  9. Selective cytotoxicity and antifungal properties of copper(II) and cobalt(II) complexes with imidazole-4-acetate anion or 1-allylimidazole
    Authors:
    Katarzyna Gałczyńska, Karol Ciepluch, Łukasz Madej, Krystyna Kurdziel, Barbara Maciejewska, Zuzanna Drulis-Kawa, Aneta Węgierek-Ciuk Anna Lankoff, Michał Arabski
    Academic press:
    Scientific Reports (rok: 2019, tom: Jul 5;9(1), strony: Jul 5;9(1):9777.), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-019-46224-6. - link to the publication
  10. Culture media composition influences the antibacterial effect of silver, cupric, and zinc ions against Pseudomonas aeruginosa
    Authors:
    Justyna Rewak-Soroczynska, Agata Dorotkiewicz-Jach *, Zuzanna Drulis-Kawa, Rafal J. Wiglusz
    Academic press:
    Biomolecules (rok: 2022, tom: 12(7), strony: 963), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biom12070963 - link to the publication
  11. Quenching of the Eu3+ Luminescence by Cu2+ Ions in the Nanosized Hydroxyapatite Designed for Future Bio-Detection
    Authors:
    Katarzyna Szyszka, Sara Targonska, Agnieszka Lewinska, Adam Watras, Rafal J. Wiglusz
    Academic press:
    Nanomaterials (rok: 2021, tom: 11, strony: 464), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  12. The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms
    Authors:
    Wojciech Zakrzewski, Maciej Dobrzynski, Joanna Nowicka, Magdalena Pajaczkowska, Maria Szymonowicz, Sara Targonska, Paulina Sobierajska, Katarzyna Wiglusz, Wojciech Dobrzynski, Adam Lubojanski, Sebastian Fedorowicz, Zbigniew Rybak and Rafal J. Wiglusz
    Academic press:
    Nanomaterials (rok: 2020, tom: 10,, strony: 1997), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano10101997 - link to the publication
  13. Antitumor Activity of Pt(II), Ru(III) and Cu(II) Complexes
    Authors:
    Katarzyna Gałczynska, Zuzanna Drulis-Kawa and Michał Arabski
    Academic press:
    Molecules (rok: 2020, tom: 25, strony: Jul 31;25(15):3492), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25153492. - link to the publication
  14. Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm
    Authors:
    Grzegorz Guła, Agata Dorotkiewicz-Jach, Kamila Korzekwa, Miguel A. Valvano, Zuzanna Drulis-Kawa
    Academic press:
    Current Medicinal Chemistry (rok: 2019, tom: 26, strony: 1979-1993), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    10.2174/0929867325666180912110151 - link to the publication
  15. Modelling experimentally measured of ciprofloxacin antibiotic diffusion in Pseudomonas aeruginosa biofilm formed in artificial sputum medium
    Authors:
    Tadeusz Kosztołowicz, Ralf Metzler, Sławomir Wa̡sik, Michał Arabski
    Academic press:
    PlosONE (rok: 2020, tom: 15, strony: Dec 3;15(12):e0243003.), Wydawca: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0243003 - link to the publication
  16. Multifunctionality of Nanosized Calcium Apatite Dual-Doped with Li+/Eu3+ Ions Related to Cell Culture Studies and Cytotoxicity Evaluation In Vitro
    Authors:
    Paulina Sobierajska, Blazej Pozniak, Marta Tikhomirov, Julia Miller, Lucyna Mrowczynska, Agata Piecuch, Justyna Rewak-Soroczynska, Agata Dorotkiewicz-Jach, Zuzanna Drulis-Kawa, Rafal J. Wiglusz
    Academic press:
    Biomolecules (rok: 2021, tom: 11, strony: 1388), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biom11091388 - link to the publication
  17. Outer Membrane Vesicles (OMVs) of Pseudomonas aeruginosa Provide Passive Resistance but Not Sensitization to LPS-Specific Phages
    Authors:
    Daria Augustyniak, Tomasz Olszak, Zuzanna Drulis-Kawa
    Academic press:
    Viruses (rok: 2022, tom: 14, strony: 121), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v14010121 - link to the publication
  18. The Application of Impedance Spectroscopy for Pseudomonas Biofilm Monitoring during Phage Infection
    Authors:
    Grzegorz Guła, Paulina Szymanowska, Tomasz Piasecki , Sylwia Góras, Teodor Gotszalk and Zuzanna Drulis-Kawa
    Academic press:
    Viruses (rok: 2020, tom: 12, strony: Apr 7;12(4):407), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v12040407 - link to the publication
  1. Przegląd badań aktywności biologicznych jonów lantanowców
    Authors:
    Justyna Rewak-Soroczyńska, Agata Dorotkiewicz-Jach, Rafał J. Wiglusz
    Conference:
    XIV Interdyscyplinarna Konferencja Naukowa TYGIEL 2022 "Interdyscyplinarność kluczem do rozwoju" konferencja Lublin/online (rok: 2022, ), Wydawca: Wydawnictwo Naukowe TYGIEL, ul. Głowackiego 35/348, 20-060 Lublin
    Data:
    konferencja 24-27.03.2022
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy