Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Effects of rapid weight gain on tylosin and enrofloxacin pharmacokinetics in turkeys - dosage modelling and validation based on pharmacokinetic-pharmacodynamic integration

2016/21/D/NZ7/01053

Keywords:

pharmacokinetics turkeys tylosin enrofloxacin integration allometry rapid weight gain walidacja

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_11: Veterinary healthcare

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Medycyny Weterynaryjnej

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Błażej Poźniak 

Number of co-investigators in the project: 3

Call: SONATA 11 - announced on 2016-03-15

Amount awarded: 214 730 PLN

Project start date (Y-m-d): 2017-01-18

Project end date (Y-m-d): 2020-01-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. zasilacz awaryjny (UPS) o mocy wyjściowej 6000VA/5400W (17 822 PLN)
  2. urządzenie klimatyzacyjne (2 900 PLN)
  3. program farmakokinetyczny Phoenix WinNonlin - dwuletnia licencja akademicka - 2019 (12 000 PLN)
  4. komputer (3 000 PLN)
  5. program farmakokinetyczny Phoenix WinNonlin - dwuletnia licencja akademicka - 2017 (12 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. The influence of age and body weight gain on enrofloxacin pharmacokinetics in turkeys—Allometric approach to dose optimization.
    Authors:
    Poźniak, B., Tikhomirov, M., Motykiewicz‐Pers, K., Bobrek, K., & Świtała, M.
    Academic press:
    Journal of Veterinary Pharmacology and Therapeutics (rok: 2020, tom: 43(1), strony: 67-78), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/jvp.12833 - link to the publication
  2. Allometric Optimization of Enrofloxacin Dosage in Growing Male Turkeys: Empirical Evidence for Improved Internal Exposure
    Authors:
    Poźniak, B., Tikhomirov, M., Motykiewicz‐Pers, K., Bobrek, K., & Świtała, M.
    Academic press:
    Antibiotics (rok: 2020, tom: 9(12), strony: 925), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antibiotics9120925 - link to the publication
  3. Allometric analysis of tylosin tartrate pharmacokinetics in growing male turkeys
    Authors:
    Poźniak, B., Tikhomirov, M., Motykiewicz‐Pers, K., Bobrek, K., & Świtała, M.
    Academic press:
    Journal of Veterinary Science (rok: 2020, tom: 21(3), strony: e35), Wydawca: Korean Society of Veterinary Science
    Status:
    Published
    DOI:
    10.4142/jvs.2020.21.e35 - link to the publication
  1. Allometric scaling of enrofloxacin dosing as a tool to optimize antibiotic use in rapidly growing turkeys
    Authors:
    Błażej Poźniak, Marta Tikhomirov, Karolina Motykiewicz-Pers, Kamila Bobrek, Piotr Okoniewski, Marcin Świtała
    Conference:
    14th International Congress of the European Association for Veterinary Pharmacology and Toxicology (rok: 2018, ), Wydawca: Wiley
    Data:
    konferencja 24-27.06.2018
    Status:
    Published

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