Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Molecular aspects of interference with the thymidylate synthase-catalyzed reaction mechanism by the slow-binding inhibitor N4-hydroxy-dCMP

2016/21/B/NZ1/00288

Keywords:

Thymidylate synthase Enzymatic catalysis Inhibition mechanism NMR QM/MM calculations

Descriptors:

  • NZ1_2: Biochemistry
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

woj. podkarpackie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Wojciech Rode 

Number of co-investigators in the project: 6

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 724 600 PLN

Project start date (Y-m-d): 2017-03-08

Project end date (Y-m-d): 2022-03-07

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.