Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Design of SERS nanosensors for ex vivo detection of inflammatory state in blood vessels

2016/21/B/ST4/02151

Keywords:

surface-enhanced Raman sensors nanosized structures immunochemistry

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_2: Spectroscopic and spectrometric techniques
  • NZ5_5: Diagnostics in human diseases

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Kamilla Małek 

Number of co-investigators in the project: 9

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 861 660 PLN

Project start date (Y-m-d): 2017-02-16

Project end date (Y-m-d): 2021-08-15

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer (6 000 PLN)
  2. Sfera całkująca z komorą pomiarową dla rejestracji widm UV-Vis ciał stałych (28 000 PLN)
  3. Elementy optyczne, elektroniczne i mechaniczne do spektrometrów (2 szt.) (10 000 PLN)
  4. Komputer (lub laptop) (4 000 PLN)
  5. Licencja Microsoft Office.
  6. laser o wzbudzeniu 632.8 nm z łącznikiem laserowym i światłowodami do spektrometru ramanowskiego (180 000 PLN)
  7. Oprogramowanie specjalistyczne (3 000 PLN)
  8. Oprogramowanie specjalistyczne (2 szt.) (6 000 PLN)
  9. przenośne dyski o pojemności > 1 TB (3 szt.) (1 200 PLN)
  10. Miernik mocy (22 328 PLN)
  11. Monitory 2 szt. (996 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. ImmunoSERS microscopy for the detection of smooth muscle cells in atherosclerotic plaques
    Authors:
    Ewelina Wiercigroch, Elzbieta Stepula, Lukasz Mateuszuk, Yuying Zhang, Malgorzata Baranska, Stefan Chlopicki, Sebastian Schlücker, Kamilla Malek
    Academic press:
    Biosensors and Bioelectronic (rok: 2019, tom: 133, strony: 79-85), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.bios.2019.02.068 - link to the publication
  2. Photocatalytical decoration of thin titania coatings with silver nanostructures provides a robust and reproducible SERS signal
    Authors:
    E. Wiercigroch, A. Kisielewska, A. Blat, A. Wislocka, I. Piwoński, K. Malek
    Academic press:
    Journal of Raman Spectroscopy (rok: 2019, tom: 50, strony: 1649-1660), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jrs.5707 - link to the publication
  3. Intracellular pH – Advantages and pitfalls of surface-enhanced Ramanscattering and fluorescence microscopy – A review
    Authors:
    Aleksandra Jaworska, Kamilla Malek, Andrzej Kudelski
    Academic press:
    Spectrochimica Acta Part A: Molecular andBiomolecular Spectroscopy (rok: 2021, tom: 251, strony: 45302), Wydawca: ScienceDirect
    Status:
    Published
    DOI:
    10.1016/j.saa.2020.119410 - link to the publication
  4. Photocatalytic deposition of plasmonic Au nanostructures on a semiconductor substrate to enhance Raman sensitivity
    Authors:
    Ewelina Wiercigroch, Pawel Swit, Aneta Kisielewska, Ireneusz Piwoński, Kamilla Malek
    Academic press:
    Applied Surface Science (rok: 2020, tom: 529, strony: 45302), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.apsusc.2020.147021 - link to the publication
  5. Detection of immune reaction by surface-enhanced Raman Spectroscopy: A mini-review
    Authors:
    Kamilla Malek, Ewelina Wiercigroch
    Academic press:
    Asian Journal of Physics (rok: 2022, tom: 31, strony: 45301), Wydawca: Anita Publications
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  6. Dual-enhancement and dual-tag design for SERS-based sandwich immunoassays: Evaluation of a metal-metal effect in 3D architecture
    Authors:
    Ewelina Wiercigroch, Pawel Swit, Agnieszka Brzozka, Łukasz Pięta, Kamilla Malek
    Academic press:
    Microchimica Acta (rok: 2022, tom: 189, strony: 32), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00604-021-05125-0 - link to the publication

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