Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Influence of prenylflavonoids from hops (Humulus lupulus L)o n hipogonadism-induced disturbances in thermoregulation and bone tissue metabolism, structure and biomechanical properties.

2016/21/B/NZ7/02759

Keywords:

hops Humulus lupulus osteoporosis hot flashes menopause prenylflavonoids xanthohumol

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • ST5_1: Structural properties of materials
  • NZ9_7: Nutrition and food sciences

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Adam Szeląg 

Number of co-investigators in the project: 14

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 719 100 PLN

Project start date (Y-m-d): 2017-05-16

Project end date (Y-m-d): 2020-05-15

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zestaw do telemetrycznego pomiaru temperatury (50 000 PLN)
  2. dyski zewnętrzne 6 TB i 8 TB (1 258 PLN)
  3. wgłębnik do mikrotwardosciomierza (9 000 PLN)
  4. membranowa pompa próżniowa przyspieszająca odparowywanie i produkcje ekstraktów (27 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (1)
  1. Synthesis and antiproliferative activity of minor hops prenylflavonoids and new insight on prenyl group cyclization
    Authors:
    Jarosław Popłoński, Eliza Turlej, Sandra Sordon, Tomasz Tronina, Agnieszka Bartmańska, Joanna Wietrzyk, Ewa Huszcza
    Academic press:
    Molecules (rok: 2018, tom: 23, strony: 776), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules23040776 - link to the publication
  2. Pharmacokinetics of xanthohumol in rats of both sexes after oral and intravenous administration of pure xanthohumol and prenylflavonoid extract.
    Authors:
    Beata Nowak, Błażej Poźniak, Jarosław Popłoński, Łukasz Bobak, Agnieszka Matuszewska, Joanna Kwiatkowska, Wojciech Dziewiszek, Ewa Huszcza, Adam Szeląg
    Academic press:
    Advances in Clinical and Experimental Medicine (rok: 2020, tom: 29 (9), strony: 1101-1109), Wydawca: Wroclaw Medical University
    Status:
    Published
    DOI:
    10.17219/acem/126293 - link to the publication
  3. Simple and green method for the extraction of xanthohumol from spent hops using deep eutectic solvents
    Authors:
    Aleksandra Grudniewska, Jarosław Popłoński
    Academic press:
    Separation and Purification Technology (rok: 2020, tom: 250, strony: 117196), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.seppur.2020.117196 - link to the publication
  4. Prenylflavonoids counteract ovariectomy-induced disturbances in rats
    Authors:
    Beata Nowak, Agnieszka Matuszewska, Jarosław Popłoński, Anna Nikodem, Jarosław Filipiak, Magdalena Tomanik, Wojciech Dziewiszek, Maciej Danielewski, Kinga Belowska-Bień, Marek Kłobucki, Sandra Sordon, Diana Jędrzejuk, Ireneusz Ceremuga, Małgorzata Trocha, Tomasz Sozański, Tomasz Piasecki, Marek Bolanowski, Ewa Huszcza, and Adam Szeląg
    Academic press:
    Journal of Functional Foods (rok: 2021, tom: 86, strony: 104742), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jff.2021.104742 - link to the publication
  1. Effect of mangiferin therapy on structural and mechanical properties of trabecular bone tissue in L4 vertebral rats
    Authors:
    Anna Nikodem, Beata Nowak, Agnieszka Matuszewska, Jarosław Filipiak
    Conference:
    Biomechanics 2018 : International Conference of the Polish Society of Biomechanics (rok: 2018, ), Wydawca: Uniwersytet Zielonogórski, Wydział Mechaniczny, Zakład Inżynierii Biomedycznej
    Data:
    konferencja 5-7. 09.2018
    Status:
    Published

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