Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Genetic determinants of psychoactive substances addiction: research on the endophenotype associated with a lack of the reward system in drug - addicted population.

2015/19/B/NZ7/03691

Keywords:

genetics addiction haplotypes

Descriptors:

  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarsko-Stomatologiczny

woj. zachodniopomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Anna Grzywacz 

Number of co-investigators in the project: 3

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 725 680 PLN

Project start date (Y-m-d): 2016-07-07

Project end date (Y-m-d): 2020-07-06

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Real Time PCR Cobas 4800 system (170 000 PLN)
  2. wirówka z chłodzeniem (50 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  1. The ankyrin repeat and kinase domain containing 1 gene polymorphism (ANKK1 Taq1A) and personality traits in addicted subjects.
    Authors:
    Grzywacz Anna, Chmielowiec Jolanta, Chmielowiec Krzysztof, Mroczek Bożena, Masiak Jolanta, Suchanecka Aleksandra, Sipak-Szmigiel Olimpia, Szumilas Kamila, Trybek Grzegorz.
    Academic press:
    Int. J. Environ. Res. Public Health (rok: 2019, tom: vol. 16, strony: 13 s. tab. bibliogr. summ.), Wydawca: Int. J. Environ. Res. Public Health
    Status:
    Published
    DOI:
    10.3390/ijerph16152687 - link to the publication
  2. The current state of research on psychiatric genetics in Poland and the world: A report covering recent years = Stan badań dotyczących genetyki psychiatrycznej w Polsce i na świecie - raport z ostatnich lat.
    Authors:
    Anna Grzywacz, Małgorzata Ryder, Iwona Małecka, Jolanta Chmielowiec.
    Academic press:
    Post. Hig. (rok: 2018, tom: vol. 72, strony: s. 1-12), Wydawca: Post. Hig.
    Status:
    Published
  3. Associations between the dopamine D4 receptor and DAT1 dopamine transporter genes polymorphisms and personality traits in addicted patients.
    Authors:
    Jolanta Chmielowiec, Krzysztof Chmielowiec, Aleksandra Suchanecka, Grzegorz Trybek, Bożena Mroczek, Iwona Małecka, Anna Grzywacz
    Academic press:
    Int. J. Environ. Res. Public Health (rok: 2018, tom: vol. 15, strony: 12 s.), Wydawca: Int. J. Environ. Res. Public Health
    Status:
    Published
    DOI:
    10.3390/ijerph15102076 - link to the publication
  4. DRD4 Exon 3 Gene Polymorphisms in Patients Diagnosed with Polysubstance Use Disorder and Co-Occurrence of a Depressive Episode
    Authors:
    Krzysztof Chmielowiec, Jolanta Chmielowiec, Jolanta Masiak, Małgorzata Czekaj, Piotr Krawczyk, Ewelina Soroka, Małgorzata Smiarowska, Wojciech Musiał, Tomasz Pawłowski, Anna Grzywacz
    Academic press:
    GENES (rok: 2021, tom: 12, 1834, strony: 14 s. tab. bibliogr. summ.), Wydawca: MDPI
    Status:
    Published
  5. Dopamine receptor DRD2 gene rs1076560, personality traits and anxiety in the polysubstance use disorder
    Authors:
    Aleksandra Suchanecka, Chmielowiec Jolanta, Chmielowiec Krzysztof, Masiak Jolanta, Sipak-Szmigiel Olimpia, Sznabowicz Mariusz, Czarny Wojciech, Michałowska-Sawczyn Monika, Trybek Grzegorz, Grzywacz Anna
    Academic press:
    Brain Sci. (rok: 2020, tom: vol. 10, strony: 12 s. tab. bibliogr. summ.), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/brainsci10050262 - link to the publication
  6. Contribution of Dopamine Transporter Gene Methylation Status to Cannabis Dependency
    Authors:
    Anna Grzywacz, Wojciech Barczak, Jolanta Chmielowiec, Krzysztof Chmielowiec, Aleksandra Suchanecka , Grzegorz Trybek , Jolanta Masiak , Paweł Jagielski , Katarzyna Grocholewicz, Blazej Rubiś
    Academic press:
    Brain Sci. (rok: 2020, tom: vol. 10, strony: 11 s. il. tab. bibliogr. summ.), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/brainsci10060400 - link to the publication
  7. Psychological factors and genetic characteristics of rural cannabis users
    Authors:
    Milena Lachowicz, Jolanta Chmielowiec, Krzysztof Chmielowiec, Aleksandra Suchanecka, Monika Michałowska-Sawczyn , Artur Mierzecki, Bożena Mroczek5, Anna Grzywacz
    Academic press:
    Ann Agric Environ Med. (rok: 2020, tom: Vol 27, strony: tab. bibliogr. summ.), Wydawca: Original Article
    Status:
    Published
    DOI:
    10.26444/aaem/119939 - link to the publication
  8. Significant association of DRD2 and ANKK1 genes with rural heroin dependence and relapse in men
    Authors:
    , Chmielowiec Jolanta, Chmielowiec Krzysztof, Suchanecka Aleksandra, Masiak Jolanta, Michałowska-Sawczyn Monika, Mroczek Bożena, Mierzecki Artur, Ciechanowicz Iwona, Grzywacz Anna
    Academic press:
    Ann. Agric. Environ. Med. (rok: 2020, tom: Vol. 27, strony: 5 s.), Wydawca: ORIGINAL ARTICLE
    Status:
    Published
    DOI:
    10.26444/aaem/119940 - link to the publication