Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular characterization of arsenic transporter Acr3

2015/19/B/NZ1/00327

Keywords:

yeast arsenic antimony antiport plasma membrane Acr3 transport protein sorting ubiquitination

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_10: Microbiology
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Maciaszczyk-Dziubińska 

Number of co-investigators in the project: 6

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 646 680 PLN

Project start date (Y-m-d): 2016-06-24

Project end date (Y-m-d): 2020-06-23

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Spectrofotometr OD600 (7 500 PLN)
  2. Wirówka z chłodzeniem (28 000 PLN)
  3. Zestaw do elektroforezy i transferu (9 500 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. The ancillary N-terminal region of the yeast AP-1 transcription factor Yap8 contributes to its DNA binding specificity
    Authors:
    Ewa Maciaszczyk-Dziubinska, Anna Reymer, Nallani Vijay Kumar, Wojciech Białek, Katarzyna Mizio, Markus J Tamás, Robert Wysocki
    Academic press:
    Nucleic Acids Research (rok: 2020, tom: 48(10), strony: 5426-5441), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkaa316 - link to the publication
  2. Ubikwitynacja, kontrola jakości i degradacja białek błonowych - szansa na terapie?
    Authors:
    Wawrzycka Donata, Mizio Katarzyna
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (rok: 2018, tom: 72, strony: 512-525), Wydawca: Index Copernicus International S.A.
    Status:
    Published
    DOI:
    10.5604/01.3001.0012.0823 - link to the publication
  3. Rsp5-dependent endocytosis and degradation of the arsenite transporter Acr3 requires its N-terminal acidic tail as an endocytic sorting signal and arrestin-related ubiquitin-ligase adaptors.
    Authors:
    Wawrzycka D., Sadlak J., Maciaszczyk-Dziubinska E., Wysocki R.
    Academic press:
    Biochimica et Biophysica Acta - Biomembranes (rok: 2019, tom: 1861(5), strony: 916-925), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2019.02.004 - link to the publication
  4. Etp1 confers arsenite resistance by affecting ACR3 expression
    Authors:
    Romero AM*, Maciaszczyk-Dziubinska E*, Mombeinipour M, Lorentzon E, Aspholm E, Wysocki R, Tamás MJ., *These authors contributed equally
    Academic press:
    FEMS Yeast Research (rok: 2022, tom: 22(1), strony: 45300), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/femsyr/foac018 - link to the publication