Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Proteolytic cleavage and turnover of dystroglycan shape synapse morphology

2015/19/B/NZ3/01376

Keywords:

dystroglycan extracellular matrix structural synaptic plasticity dendritic spines palmitoylation

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Izabela Figiel-Ożóg 

Number of co-investigators in the project: 4

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 865 000 PLN

Project start date (Y-m-d): 2016-06-20

Project end date (Y-m-d): 2020-06-19

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Elektroporator z wyposażeniem (85 000 PLN)
  2. Mikroskop odwrócony Nikon Eclipse.

Information in the final report

  • Publication in academic press/journals (4)
  1. MMP-9 signaling pathways that engage Rho GTPases in brain plasticity
    Authors:
    Izabela Figiel, Monika zaręba-Kozioł, Paulina Rybak, Monika Bijata, Jakub Włodarczyk, Joanna Dzwonek
    Academic press:
    Cells (rok: 2021, tom: 10, strony: 166), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10010166 - link to the publication
  2. Stress-induced Changes in the S-palmitoylation and S-nitrosylation of Synaptic Proteins
    Authors:
    Monika Zaręba-Kozioł, Anna Bartkowiak-Kaczmarek, Izabela Figiel, Adam Krzystyniak, Tomasz Wójtowicz, Monka Bijata, Jakub Włodarczyk
    Academic press:
    Molecular and Cellular Proteomics (rok: 2019, tom: 18, strony: 1916-1938), Wydawca: ASBMB
    Status:
    Published
    DOI:
    10.1074/mcp.RA119.001581 - link to the publication
  3. Insights Into Protein S-Palmitoylation in Synaptic Plasticity and Neurological Disorders: Potential and Limitations of Methods for Detection and Analysis.
    Authors:
    Monika Zaręba-Kozioł, Izabela Figiel, Anna Bartkowiak-Kaczmarek, Jakub Włodarczyk
    Academic press:
    Frontiers in Molecular Neuroscience (rok: 2018, tom: 11, strony: 45309), Wydawca: Frontiers Research Foundation
    Status:
    Published
    DOI:
    10.3389/fnmol.2018.00175 - link to the publication
  4. The cell adhesion protein dystroglycan affects the structural remodeling of dendritic spines
    Authors:
    Izabela Figiel, Ewa Bączyńska, Tomasz Wójtowicz, Marta Magnowska, Anna Buszka, Monika Bijata, Jakub Włodrczyk
    Academic press:
    Scientific Reports , Wydawca: Nature
    Status:
    Submitted
    DOI:
    brak - link to the publication

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