Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The mechanisms of protein targeting to the endoplasmic reticulum channels during ER-associated degradation (ERAD)

2015/19/B/NZ3/03266

Keywords:

endoplasmic reticulum membrane channels protein degradation

Descriptors:

  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Monika Słomińska-Wojewódzka 

Number of co-investigators in the project: 3

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 724 360 PLN

Project start date (Y-m-d): 2016-08-05

Project end date (Y-m-d): 2021-08-04

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Dozownik cieczy manulany.
  2. Komputer stacjonarny z oprogramowaniem i małą drukarką (4 000 PLN)
  3. Worteks laboratoryjny.
  4. Mikrowirówka bez możliwości chłodzenia wraz rotorem na probówki o pojemności 1,5-2 ml (10 000 PLN)
  5. Blok grzejny z możliwością chłodzenia prób (11 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Toxins Utilize the Endoplasmic Reticulum-Associated Protein Degradation Pathway in Their Intoxication Process
    Authors:
    Nowakowska-Gołacka J, Sominka H, Sowa-Rogozińska N, Słomińska-Wojewódzka M
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: 1307), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20061307 - link to the publication
  2. EDEM1 Regulates Amyloid Precursor Protein (APP) Metabolism and Amyloid-β Production
    Authors:
    Nowakowska-Gołacka, J.; Czapiewska, J.; Sominka, H.; Sowa-Rogozińska, N.; Słomińska-Wojewódzka, M.
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 117), Wydawca: MDPI
    Status:
    Published
    DOI:
  3. Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin
    Authors:
    1.Sowa-Rogozińska N, Sominka H, Nowakowska-Gołacka J, Sandvig K, Słomińska-Wojewódzka M.
    Academic press:
    Toxins (rok: 2019, tom: 11, strony: 350), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/toxins11060350 - link to the publication
  1. The endoplasmic reticulum (ER)-associated degradation system regulates the intracellular level of amyloid precursor protein (APP)
    Authors:
    Nowakowska-Gołacka, J.; Wróblewska, A.; Chylińska, J.; Słominska-Wojewódzka, M.
    Conference:
    The Biochemistry Global Summit, 25th IUBMB Congress, 46th FEBS Congress, 15th PABMB Congress (rok: 2022, ), Wydawca: WILEY
    Data:
    konferencja 9-14.07.
    Status:
    Published