Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of MBD3 (methyl-binding protein 3) in epileptogenesis

2015/19/B/NZ4/01401

Keywords:

epilepsy seizures DNA methylation epigenetics

Descriptors:

  • NZ4_9:
  • NZ3_5:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Katarzyna Łukasiuk 

Number of co-investigators in the project: 5

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 1 056 600 PLN

Project start date (Y-m-d): 2016-07-06

Project end date (Y-m-d): 2021-07-05

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (1)
  1. The role of methyl‑CpG binding domain 3 in seizures and epileptogenesis
    Authors:
    Karolina Nizińska, Maciej Olszewski, Dorota Nowicka, Kinga Szydłowska, Kinga Nazaruk, Katarzyna Łukasiuk
    Academic press:
    Acta Neurobiologiae Experimentalis (rok: 2025, tom: 85, strony: 67-74), Wydawca: Instytut Biologii Doświadczalnej im. Marcelego Nenckiego PAN
    Status:
    Published
    DOI:
    10.55782/ane-2025-2706 - link to the publication
  1. METHYL-CPG BINDING DOMAIN 3 PROMOTER ACTIVITY IN A RAT MODEL OF SEIZURE EVOKED BY INTRAPERITIONAL INJECTION OF PENTYLENETETRAZOL (PTZ)
    Authors:
    Karolina Nizińska, Aleksandra Stępniak, Katarzyna Łukasiuk
    Conference:
    14th International Congress of the Polish Neuroscience Society Katowice (rok: 2019, ), Wydawca: PTBUN
    Data:
    konferencja 28-30 sierpnia
    Status:
    Published