Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Deciphering the code- functional studies of noncoding sequences

2015/19/B/NZ4/03184

Keywords:

enhancer gene regulation joint formaltion limb,

Descriptors:

  • NZ4_1: Anatomy
  • NZ4_12: Other related subjects

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Przemysław Tylżanowski 

Number of co-investigators in the project: 2

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 613 867 PLN

Project start date (Y-m-d): 2016-08-17

Project end date (Y-m-d): 2021-08-16

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Lodówka laboratoryjna LKexv 3910.
  2. Zamrażarka laboratoryjna LGex 3410.
  3. Inkubator na jajka z regulowana wilgotnoscia (17 063 PLN)
  4. Wyposażenie do fluurescencji Nightsea Oświetlacz przenośny typu LED z 4 zestawami filtrów.

Information in the final report

  • Publication in academic press/journals (2)
  • Book publications / chapters in book publications (1)
  1. Mutations in gene regulatory elements linked to human limb malformations
    Authors:
    Karol Nowosad, Ewa Hordyjewska-Kowalczyk, Przemko Tylżanowski
    Academic press:
    Journal of Medical Genetics (rok: 2019, ), Wydawca: BMJ Journals
    Status:
    Published
    DOI:
    10.1136/jmedgenet-2019-106369 - link to the publication
  2. Identification of candidate enhancers controlling the transcriptome during the formation of interphalangeal joints
    Authors:
    Karol Nowosad, Rutger W. W. Brouwer, Adrian Odrzywolski, Anne L. Korporaal, Bartłomiej Gielniewski, Bartosz Wojtaś, Wilfred F. J. van IJcken, Frank Grosveld, Danny Huylebroeck, Przemko Tylzanowski
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 45307), Wydawca: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-022-16951-4 - link to the publication
  1. Low Input Targeted Chromatin Capture (Low-T2C)
    Authors:
    Ilias Boltsis, Karol Nowosad, Rutger W. W. Brouwer, Przemko Tylzanowski, Wilfred F J van IJcken, Danny Huylebroeck , Frank Grosveld, Petros Kolovos
    Book:
    Enhancers and Promoters (rok: 2021, tom: vol. 2351, strony: 165-179), Wydawca: Humana Press
    Status:
    Published