Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The influence of nanoparticles released from joint endoprosthesis on blood platelet adhesion and aggregation potential - implications for the pathogenesis of thrombo-embolic disease in patients post total hip and total knee replacements.

2015/19/D/NZ5/02189

Keywords:

adhesion aggregation nanoparticles biocorrosion blood platelets thrombosis quartz crystal microbalance with dissipation total hip replacement total knee replacement

Descriptors:

  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Krzysztof Tomaszewski 

Number of co-investigators in the project: 4

Call: SONATA 10 - announced on 2015-09-15

Amount awarded: 534 440 PLN

Project start date (Y-m-d): 2016-07-21

Project end date (Y-m-d): 2019-03-27

Project duration:: 32 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. POLOS-SPIN150i-NPP (spin coater) lub równoważny (31 000 PLN)
  2. System Agregometrii Optycznej firmy Chronolog, Model 700-2 lub równoważny (85 000 PLN)
  3. System do czyszczenia za pomocą ozonu i UV - ProCleaner Plus (BioForce Nanosciences, Inc.) lub równoważny (18 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Aluminium nanoparticles affect human platelet function in vitro
    Authors:
    Bendik Skinningsrud, Sigurd S Lauritzen, Dominik Taterra, Przemysław A Pękala, Karolina Kaczmarczyk-Sekuła, Iwona M Tomaszewska, Marek W. Radomski, Krzysztof Andrzej Tomaszewski
    Academic press:
    PeerJ (rok: 2020, tom: -, strony: -), Wydawca: PeerJ Journals
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. In vitro effects of cobalt and chromium nanoparticles on human platelet function
    Authors:
    Dominik Taterra, Bendik Skinningsrud, Przemysław A. Pękala, Iwona M. Tomaszewska, Krzysztof Marycz, Marek W. Radomski, Krzysztof A. Tomaszewski
    Academic press:
    Nanotoxicology (rok: 2020, ), Wydawca: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/17435390.2020.1841845 - link to the publication
  3. The impact of total hip arthroplasty on serum and urine aluminum levels: a metaanalysis
    Authors:
    Mitchell R. Mann, Sigurd Lauritzen, Dominik Taterra, Victoria Maria Sarata, Jakub R. Pękala, Przemysław A. Pękala, Krzysztof A. Tomaszewski
    Academic press:
    The Journal of Arthroplasty (rok: 2020, tom: -, strony: -), Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication

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