Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Application of morphological engineering techniques in the submerged cultures of filamentous fungi

2015/19/B/ST8/02115

Keywords:

morphological engneering microparticle-enhanced cultivation filamentous fungi digital image analysis bioreactor

Descriptors:

  • ST8_1: Chemical engineering, technical chemistry, environmental engineering, sanitary engineering, engineering of chemical processes
  • ST8_13: Architectural acoustics

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Politechnika Łódzka, Wydział Inżynierii Procesowej i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marcin Bizukojć 

Number of co-investigators in the project: 4

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 532 800 PLN

Project start date (Y-m-d): 2016-06-14

Project end date (Y-m-d): 2019-06-13

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mikroskop świetlny z kamerą i oprogramowanie do cyfrowej analizy obrazu (180 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (3)
  1. Exploring the extremes: applying high concentration of yeast extract leads to drastic morphological changes and elimination of (+)-geodin and asterric acid production in Aspergillus terreus submerged cultures
    Authors:
    Tomasz Boruta, Adrianna Górnicka, Iwona Grzybowska, Ida Stefaniak, Marcin Bizukojć
    Academic press:
    Biotechnology Letters (rok: 2021, tom: 43, strony: 61-71), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10529-020-03018-5 - link to the publication
  2. Application of aluminum oxide nanoparticles in Aspergillus terreus cultivations: evaluating the effects on lovastatin production and fungal morphology
    Authors:
    Tomasz Boruta, Marcin Bizukojć
    Academic press:
    BioMed Research International (rok: 2019, tom: ID 5832496, strony: 45302), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2019/5832496 - link to the publication
  3. Kinetic model to describe the morphological evolution of filamentous fungi during their early stages of growth in the standard submerged and microparticle-enhanced cultivations.
    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Academic press:
    Engineering in Life Sciences (rok: 2019, tom: 19, strony: 557-574), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/elsc.201900013 - link to the publication
  4. Bioprocess-related, morphological and bioinformatic perspectives on the biosynthesis of secondary metabolites produced by Penicillium solitum.
    Authors:
    Boruta T., Przerywacz P., Ryngajłło M., Bizukojć M.
    Academic press:
    Process Biochemistry (rok: 2018, tom: 68, strony: 45647), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.procbio.2018.02.023 - link to the publication
  5. Porównanie form morfologicznych grzybni A. terreus i M. racemosus w hodowlach wgłębnych
    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Academic press:
    Acta Scientarum Polonorum Biotechnologia (rok: 2018, tom: 17(3), strony: 43-50), Wydawca: Uniwersytet Przyrodniczy we Wrocławiu
    Status:
    Published
    DOI:
    10.30825/5.biot.65.2018.17.3 - link to the publication
  6. Morphological evolution of various fungal species in the presence and absence of aluminum oxide microparticles: Comparative and quantitative insights into microparticle-enhanced cultivation (MPEC)
    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Academic press:
    MicrobiologyOpen (rok: 2018, tom: 7(5), strony: e00603), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/mbo3.603 - link to the publication
  7. Performance of fungal microparticle-enhanced cultivations in stirred tank bioreactors depends on species and number of process stages.
    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Academic press:
    Biochemical Engineering Journal (rok: 2020, tom: 161, strony: 107696), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bej.2020.107696 - link to the publication
  8. Techniki inżynierii morfologicznej dla zwiększania wydajności tworzenia metabolitów przez grzyby strzępkowe w hodowlach wgłębnych
    Authors:
    Marcin Bizukojć
    Academic press:
    Przemysł Chemiczny (rok: 2017, tom: 96/3, strony: 645-649), Wydawca: SIGMA NOT
    Status:
    Published
    DOI:
    brak - link to the publication
  1. Microparticle-enhanced cultivation of filamentous fungi – insight into the action of microparticles towards various fungal species
    Authors:
    Marcin Bizukojć, Anna Kowalska, Tomasz Boruta
    Conference:
    ECB18 18th Eurpean Congress on Biotechnology, Genewa, Szwajcaria (rok: 2018, ), Wydawca: Elsevier, Abstracts/New Biotechnology
    Data:
    konferencja 1-4 lipca 2018
    Status:
    Published
  2. Kinetic model describing the early stages of morphological evolution of various filamentous fungi species
    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Conference:
    ECB18 18th European Congress on Biotechnology, Genewa, Szwajcaria (rok: 2018, ), Wydawca: Elsevier, Abstracts/New Biotechnology
    Data:
    konferencja 1-4 lipca 2018
    Status:
    Published
  3. Production of secondary metabolites by Aspergillus terreus cocultivated with Chaetomium globosum under submerged conditions
    Authors:
    Tomasz Boruta, Iwona Milczarek, Marcin Bizukojć
    Conference:
    ECB18 18th European Congress on Biotechnology, Genewa, Szwajcaria (rok: 2018, ), Wydawca: Elsevier, Abstracts/New Biotechnology
    Data:
    konferencja 1-4 lipca 2018
    Status:
    Published

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