Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Clinical, biochemical and genetic factros for response to antibody anti-IgE treatment in asthma phenotypes

2015/19/B/NZ5/00096

Keywords:

asthma asthma phenotypes antibody anti-IgE aspirin desensitization

Descriptors:

  • NZ5_5: Diagnostics in human diseases
  • NZ6_2: Clinical immunology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Lucyna Mastalerz 

Number of co-investigators in the project: 8

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 1 106 753 PLN

Project start date (Y-m-d): 2016-10-05

Project end date (Y-m-d): 2020-04-04

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Chłodziarko-zamrażarka (2 999 PLN)
  2. Aparat Luminex 200 (273 310 PLN)
  3. Pipety.
  4. Wytrząsarka do mikro płytek (1 570 PLN)
  5. Zasilacz UPS.

Information in the final report

  • Publication in academic press/journals (7)
  1. Artificial neural network identifies nonsteroidal anti-inflammatory drugs exacerbated respiratory disease (N-ERD) cohort.
    Authors:
    Katarzyna Ewa Tyrak, Kinga Pajdzik, Ewa Konduracka, Adam Ćmiel, Bogdan Jakieła, Natalia Celejewska-Wójcik, Gabriela Trąd, Adrianna Kot, Anna Urbańska, Ewa Zabiegło, Radosław Kacorzyk, Izabela Kupryś-Lipińska, Krzysztof Oleś, Piotr Kuna, Marek Sanak, Lucyna Mastalerz.
    Academic press:
    Allergy (rok: 2020, tom: Epub, strony: Epub), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/all.14214. - link to the publication
  2. Non‐eosinophilic asthma in nonsteroidal anti‐inflammatory drug exacerbated respiratory disease
    Authors:
    Lucyna Mastalerz, Natalia Celejewska‐Wójcik, Adam Ćmiel, Krzysztof Wójcik, Joanna Szaleniec. Jerzy Tomik, Marek Sanak
    Academic press:
    Clinical and Translational Allergy (rok: 2023, tom: Epub, strony: Epub), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/clt2.12235 - link to the publication
  3. Peripheral biomarkers for predicting sputum eosinophilia in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease
    Authors:
    Gabriela Trąd, Marek Sanak, Adam Ćmiel, Natalia Celejewska-Wójcik, Michał Czekaj, Lucyna Mastalerz
    Academic press:
    Allergy (rok: 2023, tom: Epub, strony: Epub), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/all.15780 - link to the publication
  4. Subphenotypes of NSAID-exacerbated respiratory disease identified by latent class analysis.
    Authors:
    Natalia Celejewska-Wójcik, Krzysztof Wójcik, Maria Ignacak-Popiel, Adam Ćmiel, Katarzyna Tyrak, Anna Gielicz, Aleksander Kania, Paweł Nastałek, Marek Sanak, Lucyna Mastalerz.
    Academic press:
    Allergy (rok: 2020, tom: 75, strony: 831-840), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/all.14141. - link to the publication
  5. Sputum biomarkers during aspirin desensitization in nonsteroidal anti-inflammatory drugs exacerbated respiratory disease.
    Authors:
    Katarzyna Ewa Tyrak, Izabela Kupryś-Lipińska, Ewa Czarnobilska, Bogdan Jakieła, Kinga Pajdzik, Adam Ćmiel, Hanna Plutecka, Mateusz Koziej, Aleksandra Gawrońska, Ewa Konduracka, Piotr Kuna, Marek Sanak, Lucyna Mastalerz.
    Academic press:
    Respiratory Medicine (rok: 2019, tom: 152, strony: 51-59), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.rmed.2019.04.021. - link to the publication
  6. Biomarkers for predicting response to aspirin therapy in aspirin-exacerbated respiratory disease.
    Authors:
    Tyrak KE, Pajdzik K, Jakieła B, Kupryś-Lipińska I, Ćmiel A, Kacorzyk R, Trąd G, Kuna P, Sanak M, Mastalerz L.
    Academic press:
    Clin Exp Allergy (rok: 2021, tom: 51(8), strony: 1046-1056), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/cea.13886. - link to the publication
  7. Sputum transcriptome analysis of co-regulated genes related to arachidonic acid metabolism in N-ERD
    Authors:
    Lucyna Mastalerz, Radosław Kacorzyk, Bogdan Jakieła, Adam Ćmiel, Marek Sanak
    Academic press:
    Allergy (rok: 2022, tom: Epub, strony: Epub), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/all.15501 - link to the publication

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