Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Drug transporters and their regulation in liver pathology

2015/18/M/NZ7/00410

Keywords:

drug transporters liver pathology

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Medycyny i Stomatologii

woj. zachodniopomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marek Droździk 

Number of co-investigators in the project: 5

Call: HARMONIA 7 - announced on 2015-06-15

Amount awarded: 1 103 964 PLN

Project start date (Y-m-d): 2016-04-11

Project end date (Y-m-d): 2021-04-10

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Identifying differentially expressed microRNAs, target genes and key pathways deregulated in patients with liver diseases
    Authors:
    Gholizadeh M., Szelag-Pieniek S., Post M., Kurzawski M., Prieto J., Argemi J., Drozdzik M., Kaderali L
    Academic press:
    Int. J. Mol. Sci. (rok: 2020, tom: 21, strony: 7368), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21197368 - link to the publication
  2. The reference liver – ABC and SLC drug transporters in healthy donor and metastatic livers
    Authors:
    Kurzawski M., Szeląg-Pieniek S., Łapczuk-Romańska J., Wrzesiński M., Sieńko J., Oswald S., Droździk M
    Academic press:
    Pharmacol Rep. (rok: 2019, tom: 71, strony: 738-745), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1016/j.pharep.2019.04.001 - link to the publication
  3. Extrahepatic drug transporters in liver failure: focus on kidney and gastrointestinal tract
    Authors:
    Droździk M., Oswald S., Drozdzik A
    Academic press:
    Int. J. Mol. Sci. (rok: 2020, tom: 21, strony: 5737), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21165737 - link to the publication
  4. Protein abundance of hepatic drug transporters in patients with different forms of liver damage
    Authors:
    Marek Drozdzik, Sylwia Szelag-Pieniek, Mariola Post, Samir Zeair, Maciej Wrzesinski, Mateusz Kurzawski, Jesus Prieto, Stefan Oswald
    Academic press:
    Clinical Pharmacology and Therapeutics (rok: 2020, tom: 107, strony: 1138-1148), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/cpt.1717 - link to the publication