Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of JAK-STAT pathway in reverting of MDR phenotype by oncostatin M

2015/17/D/NZ7/00814

Keywords:

JAK-STAT oncostatin M ABCC1 ABCG2 ABCB1

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Andrzej Błauż 

Number of co-investigators in the project: 3

Call: SONATA 9 - announced on 2015-03-16

Amount awarded: 426 200 PLN

Project start date (Y-m-d): 2016-01-28

Project end date (Y-m-d): 2020-01-27

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Oncostatin M reverses ABCG2-mediated mitoxantrone resistance
    Authors:
    A. Błauż,, M. Wachulec, B. Rychlik
    Academic press:
    Biomedicine & Pharmacotherapy   (rok: 2024, tom: 176, strony: 116861), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2024.116861 - link to the publication
  2. Inhibitor aktywności transportera ABCC1 do zastoswania w leczeniu inwazyjnych stadiów nowotworu poprzez hamowanie ich zdolności inwazyjnych oraz kompozycja farmaceutyczna zawierająca taki inhibitor
    Authors:
    W. Ciszewski, K. Sobierajska, A. Błauż
    Academic press:
    Urząd Patentowy Rzeczpospoitej Polskiej , Wydawca: Urząd Patentowy Rzeczpospolitej Polskiej
    Status:
    Submitted