Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Biological function of the molecular chaperone ClpB (Hsp100) from the bacterium Leptospira interrogans, the etiologic agent of leptospirosis

2015/17/N/NZ6/03493

Keywords:

ClpB molecular chaperone leptospirosis pathogen

Descriptors:

  • NZ6_4: Bacteriology
  • NZ6_3: Animal immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Joanna Krajewska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 149 800 PLN

Project start date (Y-m-d): 2016-01-20

Project end date (Y-m-d): 2019-01-19

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mikrowirówka z systemem chłodzącym i rotorem (Eppendorff) (25 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (5)
  1. Immunoreactivity of the AAA+ chaperone ClpB from Leptospira interrogans with sera from Leptospira-infected animals
    Authors:
    Joanna Krajewska, Zbigniew Arent, Daniel Więckowski, Michal Zolkiewski, Sabina Kędzierska-Mieszkowska
    Academic press:
    BMC Microbiology (rok: 2016, tom: 16, strony: 151), Wydawca: BioMed Central The Open Access Publisher
    Status:
    Published
    DOI:
    10.1186/s12866-016-0774-8 - link to the publication
  2. Characterization of the molecular chaperone ClpB from the pathogenic spirochaete Leptospira interrogans
    Authors:
    Joanna Krajewska, Anna Modrak-Wójcik,Zbigniew J. Arent, Daniel Więckowski, Michal Zolkiewski, Agnieszka Bzowska, Sabina Kędzierska-Mieszkowska
    Academic press:
    PLoS One (rok: 2017, tom: 12, strony: 45312), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0181118 - link to the publication
  3. Isolation and identification of putative protein substrates of the AAA+ molecular chaperone ClpB from the pathogenic spirochaete
    Authors:
    Joanna Krajewska, Zbigniew Arent, Michal Zolkiewski, Sabina Kedzierska-Mieszkowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2018, tom: 19, strony: 1234), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19041234 - link to the publication
  1. Charakterystyka białka opiekuńczego ClpB (Hsp100) pochodzącego z patogennej bakterii Leptospira interrogans, czynnika etiologicznego leptospirozy
    Authors:
    Joanna Krajewska, Zbigniew Arent, Anna Modrak-Wójcik, Daniel Więckowski, Agnieszka Bzowska, Sabina Kędzierska-Mieszkowska
    Conference:
    I Ogólnopolska Mikrobiologiczna Konferencja Naukowa Microbs (rok: 2016, ), Wydawca: Fundacja na rzecz promocji nauki i rozwoju Tygiel
    Data:
    konferencja 12-13.05.2016
    Status:
    Published
  2. Rola dezagregazy ClpB w wirulencji patogenów bakteryjnych
    Authors:
    Joanna Krajewska, Zbigniew Arent, Sabina Kędzierska-Mieszkowska
    Conference:
    II Ogólnopolska Mikrobiologiczna Konferencja Naukowa Microbs (rok: 2017, ), Wydawca: Fundacja na rzecz promocji nauki i rozwoju TYGIEL
    Data:
    konferencja 18-19.04.2017
    Status:
    Published
  3. Trapping and identification of potential substrates of the molecular chaperone ClpB (Hsp100) from the pathogenic bacterium Leptospira interrogans
    Authors:
    Joanna Krajewska, Zbigniew Arent, Sabina Kędzierska-Mieszkowska
    Conference:
    3rd ELS Scientific Meeting on leptospirosis and other rodent borne haemorrhagic fevers (rok: 2018, ), Wydawca: Nuova Stampa Color srl
    Data:
    konferencja 24-26.05.2018
    Status:
    Published
  4. A proteomic approach for screening potential substrates of the molecular chaperone ClpB from Leptospira interrogans
    Authors:
    Joanna Krajewska, Zbigniew Arent, Sabina Kędzierska-Mieszkowska
    Conference:
    I Konferencja - Naukowa Jesień w UCMW "Infekcyjne czynniki etiologiczne XXI wieku-wspólny problem ludzi i zwierząt" (rok: 2017, ), Wydawca: Wydawnictwo Uniwersytetu Rolniczego w Krakowie
    Data:
    konferencja 29-30.09.2017
    Status:
    Published
  5. Identification of putative protein substrates for the molecular chaperone ClpB in the pathogenic bacterium Leptospira interrogans
    Authors:
    Joanna Krajewska, Zbigniew Arent, Daniel Więckowski, Sabina Kędzierska-Mieszkowska
    Conference:
    X Parnas Conference Young Scientist Forum "Molecules in the Living Cell and Innovative Medicine" (rok: 2016, ), Wydawca: Acta Biochemica Polonica
    Data:
    konferencja 10-12.07.2016
    Status:
    Published