Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New MOF compounds as degradable nanocontainers of tyrosine kinases inhibitors in novel anti-cancer therapy

2015/17/B/ST5/01446

Keywords:

MOF cystine TCPP H3TCBPB biologically friendly MOF anti-cancer therapy

Descriptors:

  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • ST5_8: Metals, alloys

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Mikołaja Kopernika, Wydział Chemii

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Artur Terzyk 

Number of co-investigators in the project: 8

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 730 080 PLN

Project start date (Y-m-d): 2016-03-17

Project end date (Y-m-d): 2020-05-16

Project duration:: 50 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zestaw do HPLC (150 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (8)
  1. Cystine-based MBioF for Maintaining the Antioxidant-oxidant Balance in Airways Diseases
    Authors:
    M. Wiśniewski, A. Bieniek, K. Roszek, J. Czarnecka, P. Bolibok, P. Ferrer, I. Da Silva, A.P. Terzyk
    Academic press:
    ACS Med. Chem. Lett. (rok: 2018, tom: 9, strony: 1280-1284), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsmedchemlett.8b00468 - link to the publication
  2. Mechanistic aspects of water adsorption – desorption in porphyrin containing MOFs
    Authors:
    M. Wiśniewski, A. Bieniek, P. Bolibok, S. Koter, P. Bryk, P. Kowalczyk, A. P. Terzyk
    Academic press:
    Microporous & Mesoporous Materials (rok: 2019, tom: 290, strony: 109649, 1-8), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.micromeso.2019.109649 - link to the publication
  3. MOF materials as therapeutic agents, drug carriers, imaging agents and biosensors in cancer biomedicine: recent advances and perspectives
    Authors:
    Adam Bieniek, Artur Terzyk, Marek Wiśniewski, Katarzyna Roszek, Piotr Kowalczyk, Lev Sarkisov, Seda Keskin, Katsumi Kaneko
    Academic press:
    Progr. Mater. Sci. (rok: 2021, tom: 117, strony: 100743), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pmatsci.2020.100743 - link to the publication
  4. Non-thermal plasma-assisted catalytic CO2 conversion over Zn-TCPP 2D catalyst
    Authors:
    Marek Wiśniewski, Artur P. Terzyk
    Academic press:
    Adsorption (rok: 2020, tom: 26, strony: 1165-1171), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10450-020-00222-7 - link to the publication
  5. New Strategy of Controlled, Stepwise Release from Novel MBioF and its Potential Application for Drug Delivery Systems
    Authors:
    M. Wiśniewski, A. Bieniek, K. Roszek, P. Bolibok, A.P. Terzyk, P. Ferrer, I. Da Silva
    Academic press:
    Adsorption (rok: 2019, tom: 25, strony: 383–391), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10450-018-00002-4 - link to the publication
  6. Stability of Coordination Polymers in Water - State of the Art and Towards a Methodology for Nonporous Materials
    Authors:
    A.P. Terzyk, A. Bieniek, P. Bolibok, M. Wiśniewski, P. Ferrer, I. Da Silva, P. Kowalczyk
    Academic press:
    Adsorption (rok: 2019, tom: 25, strony: 45302), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10450-018-9991-9 - link to the publication
  7. Testing the Self-cleaning Properties of a Coordination Polymer Surface
    Authors:
    A.P. Terzyk, G. Szymański, E. Korczeniewski, P. Bryk, A. Bieniek, P. Bolibok, M. Chodkowski, P. Kowalczyk, M. Wiśniewski, P. Ferrer, I. Da Silva
    Academic press:
    Adsorption (rok: 2019, tom: 25, strony: 33-39), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10450-018-9987-5 - link to the publication
  1. Wielofunkcyjne układy z MOF w medycynie
    Authors:
    A. Bieniek, M. Wiśniewski, P. Bolibok, A.P. Terzyk
    Conference:
    NanoBioMateriały teoria i praktyka 2017 (rok: 2017, ), Wydawca: Wydawnictwo Naukowe Uniwersytetu Mikołaja Kopernika
    Data:
    konferencja 29-31.05.2017
    Status:
    Published
  2. Hydrotermalna stabilność MOF złożonego z cynku i porfiryny Zn2(ZnTCPP)
    Authors:
    Adam Bieniek, Marek Wiśniewski, Artur P. Terzyk
    Conference:
    NanoBioMateriały teoria i praktyka 2016 (rok: 2019, ), Wydawca: Wydawnictwo Naukowe UMK w Toruniu
    Data:
    konferencja 43622
    Status:
    Published
  3. Nowe MBioF: Zn(Cys)2, Mg(Cys)2, Ca(Cys)2 porównanie właściwości fizykochemicznych i biologicznych
    Authors:
    Bieniek Adam, Wiśniewski Marek, Terzyk Artur P.
    Conference:
    NanoBioMateriały - teoria i praktyka (rok: 2018, ), Wydawca: Uniwersytet Mikołaja Kopernika
    Data:
    konferencja 6-8.06
    Status:
    Published
  4. Potential application of Zn(Cys)2 as drug delivery system with controlled, stepwise release
    Authors:
    Bieniek Adam, Wiśniewski Marek, Terzyk Artur P., Bolibok Paulina, Roszek Katarzyna
    Conference:
    Symposium on Metal-Organic Frameworks and Porous Organic Materials (rok: 2018, ), Wydawca: University of Southampton, 2018
    Data:
    konferencja 9-10.04
    Status:
    Published
  5. Mechanism of H2O interaction with Pillarless Porphyrin-based Coordination Polymers
    Authors:
    Marek Wiśniewski, Adam Bieniek, Paulina Bolibok, Artur P. Terzyk, Pilar Ferrer, Ivan da Silva and Piotr Kowalczyk
    Conference:
    Fundamentals of Adsorption 2019 (rok: 2019, ), Wydawca: International Adsorption Society
    Data:
    konferencja 43611
    Status:
    Published
  6. Nowy porowaty związek cystyny i cynku jako przykład MBioF
    Authors:
    Adam Bieniek, Marek Wiśniewski, Artur Piotr Terzyk
    Conference:
    NanoBioMateriały teoria i praktyka 2016 (rok: 2016, ), Wydawca: Wydawnictwo Naukowe Uniwersytetu Mikołaja Kopernika
    Data:
    konferencja 2-3 czerwca
    Status:
    Published
  7. Anti-oxidative properties of various metal ions (Zn, Mg, Ca) in cystine-coordination-polymers.
    Authors:
    Bieniek Adam, Wiśniewski Marek, Bolibok Paulina, Czarnecka Joanna, Roszek Katarzyna, Terzyk Artur P.
    Conference:
    Effects of surface heterogeneity in adsorption, catalysis and related phenomena : Tenth International Symposium (rok: 2018, ), Wydawca: Faculty of Chemistry. Maria Curie-Skłodowska University
    Data:
    konferencja 27-31.08
    Status:
    Published
  8. The intelligent MBioF and its potential application for drug delivery systems
    Authors:
    Wiśniewski Marek, Bieniek Adam, Bolibok Paulina, Ferrer Pilar, da Silva Ivan, Włoch Jerzy, Terzyk Artur P.
    Conference:
    Effects of surface heterogeneity in adsorption, catalysis and related phenomena : Tenth International Symposium (rok: 2018, ), Wydawca: Faculty of Chemistry. Maria Curie-Skłodowska University
    Data:
    konferencja 27-31.08
    Status:
    Published

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