Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Effectiveness of new lipofection mixtures containing polyisoprenoid derivatives in overexpressing vascular endothelial growth factor (VEGF-A): impact on blood pressure of spontaneously hypertensive rats

2015/17/N/NZ4/02831

Keywords:

cationic derivatives of polyisoprenoid alcohols expression of vascular endothelial growth factor hypertension

Descriptors:

  • NZ4_4: Pathophysiology
  • NZ1_5: Genetic engineering
  • NZ4_2: Physiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Olga Gawryś 

Number of co-investigators in the project: 3

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2016-02-25

Project end date (Y-m-d): 2019-02-24

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Polyprenol-Based Lipofecting Agents for In Vivo Delivery of Therapeutic DNA to Treat Hypertensive Rats
    Authors:
    Olga Gawrys, Monika Rak, Iwona Baranowska, Sylwia Bobis-Wozowicz, Karolina Szaro, Zbigniew Madeja, Ewa Swiezewska, Marek Masnyk, Marek Chmielewski, Elzbieta Karnas, Elzbieta Kompanowska-Jezierska
    Academic press:
    Biochemical Genetics (rok: 2020, tom: 45510, strony: 45312), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10528-020-09992-9 - link to the publication