Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The role of the WWOX gene in neuronal differentiation mechanisms

2015/17/D/NZ2/01989

Keywords:

WWOX neuronal differentiation apoptosis

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_7: Bioinformatics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Kośla 

Number of co-investigators in the project: 5

Call: SONATA 9 - announced on 2015-03-16

Amount awarded: 420 600 PLN

Project start date (Y-m-d): 2016-03-09

Project end date (Y-m-d): 2021-03-08

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Loss of Wwox Perturbs Neuronal Migration and Impairs Early Cortical Development
    Authors:
    Michele Iacomino, Simona Baldassari, Yuki Tochigi, Katarzyna Kośla, Francesca Buffelli, Annalaura Torella, Mariasavina Severinp, Dario Paladini, Luana Mandarà, Antonella Riva, Marcello Scala, Ganna Balagura, Andrea Accogli, Vincenzo Nigro, Carlo Minetti, Ezio Fulcheri, Federico Zara, Andrzej K Bednarek, Pasquale Striano, Hiroetsu Suzuki, Vincenzo Salpietro
    Academic press:
    Frontiers in Neuroscience (rok: 2020, tom: 14, strony: 644), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnins.2020.00644 - link to the publication
  2. The WWOX Gene Influences Cellular Pathways in the Neuronal Differentiation of Human Neural Progenitor Cells
    Authors:
    Katarzyna Kośla, Elżbieta Płuciennik, Ewa Styczeń-Binkowska, Magdalena Nowakowska, Magdalena Orzechowska, Andrzej K. Bednarek
    Academic press:
    Frontiers in Cellular Neuroscience (rok: 2019, tom: 13, strony: 319), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fncel.2019.00391 - link to the publication
  3. The WWOX gene in brain development and pathology
    Authors:
    Katarzyna Kośla, Żaneta Kałuzińska, Andrzej K. Bednarek
    Academic press:
    Experimental Biology and Medicine (rok: 2020, tom: 245, strony: 1122–1129), Wydawca: Sage Journals
    Status:
    Published
    DOI:
    10.1177/1535370220924618 - link to the publication
  1. The WWOX gene depletion impairs neural cell migration process and may disrupt brain development
    Authors:
    K. Kośla, E. Płuciennik, M. Orzechowska, D. Jędroszka, I. Baryła, R. Hammouz, E. Styczeń-Binkowska, A. K. Bednarek
    Conference:
    The FEBS Congress 2019 (rok: 2019, ), Wydawca: The Federation of European Biochemical Societies FEBS Press
    Data:
    konferencja 6-11.07.2019
    Status:
    Published
  2. Novel role of WWOX tumor suppressor gene in regulation of brain cells differentiation
    Authors:
    Kośla K., Styczeń-Binkowska E., Nowakowska M., Płuciennik E., Pospiech K., Baryła I., Jędroszka D., Orzechowska M., Bednarek A. K.
    Conference:
    XXth Gliwice Scientific Meetings 2016 (rok: 2016, ), Wydawca: Association for the Support of Cancer Research Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch Silesian University of Technology
    Data:
    konferencja 18-19 Listopada 2016
    Status:
    Published