Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of neutrophil extracellular traps and mammalian target of rapamycin complex (mTORc) in the ethiopathogenesis of antiphospholipid syndrome and anti-PR3 associated vasculitis.

2015/17/B/NZ6/03459

Keywords:

neutrophil extracellular traps (NETs) antiphospholipid syndrome vasculitis antibodies againts proteinase 3 mammalian target of rapamycin complex

Descriptors:

  • NZ6_2: Clinical immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jacek Musiał 

Number of co-investigators in the project: 9

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 1 061 160 PLN

Project start date (Y-m-d): 2016-02-12

Project end date (Y-m-d): 2019-08-11

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Fibrintimer (15 000 PLN)
  2. Filtry do mikroskopu (42 000 PLN)
  3. Czytnik do mikropłytek (93 000 PLN)
  4. QIAvac-24-PLUS system (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Reduced plasma fibrin clot permeability is associated with recurrent thromboembolic events in patients with antiphospholipid syndrome
    Authors:
    Magdalena Celińska-Lowenhoff, Michał Ząbczyk, Teresa Iwaniec, Krzysztof Plens, Jacek Musiał, Anetta Undas
    Academic press:
    Rheumatology (Oxford) (rok: 2018, tom: 57, strony: 1340-1349), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/rheumatology/key089. - link to the publication
  2. Delayed neutrophil apoptosis in granulomatosis with polyangiitis: dysregulation of neutrophil gene signature and circulating apoptosis-related proteins
    Authors:
    Surmiak M, Hubalewska-Mazgaj M, Wawrzycka-Adamczyk K, Musiał J and Sanak M
    Academic press:
    Scandinavian Journal of Rheumatology (rok: 2020, tom: 49, strony: 57-67), Wydawca: Taylor & Francis Online
    Status:
    Accepted for publication
    DOI:
    10.1080/03009742.2019.1634219 - link to the publication

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