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Information of the project and the call

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Globalna analiza miRNA w monocytach od pacjentów z reumatoidalnym zapaleniem stawów i twardziną układową

2015/16/S/NZ6/00041

Keywords:

Descriptors:

  • NZ6_2: Clinical immunology
  • NZ1_1: Molecular biology
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji im. prof. dr hab. med. Eleonory Reicher

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marzena Ciechomska 

Number of co-investigators in the project: 2

Call: FUGA 4 - announced on 2014-12-15

Amount awarded: 612 000 PLN

Project start date (Y-m-d): 2015-12-01

Project end date (Y-m-d): 2019-11-29

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (4)
  1. The role of microRNA-5196 in the pathogenesis of systemic sclerosis.
    Authors:
    Ciechomska M, Zarecki P, Merdas M, Swierkot J, Morgiel E, Wiland P, Maslinski W, Bogunia-Kubik K
    Academic press:
    European Journal of Clinical Investigation (rok: 2017, tom: 47(8), strony: 555-564), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1111/eci.12776. - link to the publication
  2. IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics
    Authors:
    O'Reilly S, Ciechomska M, Fullard N, Przyborski S, van Laar JM
    Academic press:
    Scientific Reports (rok: 2016, tom: 26, strony: 45304), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/srep25066 - link to the publication
  3. DNA Methylation as a Future Therapeutic and Diagnostic Target in Rheumatoid Arthritis.
    Authors:
    Ciechomska M, Roszkowski L, Maslinski W.
    Academic press:
    Cells (rok: 2019, tom: 8(9), strony: 45307), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells8090953 - link to the publication
  4. Global miRNA and mRNA expression profiles identify miRNA-26a-2-3p-dependent repression of IFN signature in systemic sclerosis human monocytes
    Authors:
    Ciechomska M, Wojtas B, Swacha M, Olesinska M, Benes V, Maslinski W
    Academic press:
    European Journal of Immunology (rok: 2020, tom: 50, strony: 1057-1066), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/eji.201948428 - link to the publication
  5. Epigenetic Modulation as a Therapeutic Prospect for Treatment of Autoimmune Rheumatic Diseases
    Authors:
    Ciechomska M, O'Reilly S
    Academic press:
    Mediators of Inflammation (rok: 2016, tom: V 2016; 2016, strony: 45302), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10. - link to the publication
  6. Targeting interferons as a strategy for systemic sclerosis treatment.
    Authors:
    Ciechomska M, Skalska U.
    Academic press:
    Immunology Letters (rok: 2017, tom: 195, strony: 45-54), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.011. - link to the publication
  7. Changes in MiRNA-5196 Expression as a Potential Biomarker of Anti-TNF-α Therapy in Rheumatoid Arthritis and Ankylosing Spondylitis Patients
    Authors:
    Ciechomska M, Bonek K, Merdas M, Zarecki P, Swierkot J, Gluszko P, Bogunia-Kubik K, Maslinski W
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (rok: 2018, tom: Volume 66, strony: 389–397), Wydawca: Springer
    Status:
    Accepted for publication
    DOI:
    389–397 - link to the publication
  1. Identification of novel micrornas in monocytes from rheumatoid arthritis and systemic sclerosis patients using next generation sequencing
    Authors:
    Marzena Ciechomska1, Krzysztof Bonek1, Anna Plaza1, Piotr Gluszko1, Monika Swacha1, Marzena Olesinska1, Bettina Haase2, Vladimir Benes2, Bartosz Wojtas3, Bozena Kaminska3, Wlodzimierz Maslinski1
    Conference:
    37th European Workshop for Rheumatology Research (rok: 2017, ), Wydawca: BMJ Publishing Group Ltd
    Data:
    konferencja 2 – 4 Marzec
    Status:
    Published
    DOI:
    link to the publication
  2. Epigenetic modifications and TLR8 signaling contribute to systemic sclerosis pathogenesis by ROS and profibrotic genes induction
    Authors:
    Ciechomska M, Zarecki P, Piatek D, Merdas M, Swierkot J, Morgiel E, van Laar JM, Maslinski W and Bogunia-Kubik K
    Conference:
    36th European Workshop for Rheumatology Research (rok: 2016, ), Wydawca: BMJ Publishing Group Ltd
    Data:
    konferencja 25-27 Luty
    Status:
    Published
    DOI:
    link to the publication
  3. The role of miRNA in type I IFN signature in monocytes of patients with systemic sclerosis
    Authors:
    M. Ciechomska , M. Olesinska , B. Wojtas, W. Maslinski
    Conference:
    FEBS Congres (rok: 2019, ), Wydawca: FEBS Open Bio
    Data:
    konferencja 6-11 lipca
    Status:
    Published
    DOI:
    link to the publication
  4. Global Mirna Expression and Transcriptomic Profiling of Monocytes from RA Patients
    Authors:
    Marzena Ciechomska, Krzysztof Bonek, Piotr Gluszko, Vladimir Benes, Bartosz Wojtas, Wlodzimierz Maslinski
    Conference:
    2018 ACR/ARHP Annual Meeting - American College of Rheumatology, (rok: 2018, ), Wydawca: Willey
    Data:
    konferencja 19-24 Październik
    Status:
    Published
    DOI:
    link to the publication

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