Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Nano-aggregates polycation-polyanion as a new type of drug carriers - characterization of biological and physicochemical properties.

2014/15/D/ST4/02770

Keywords:

nanoaggregates polysaccharides polycations polyanions drud carriers piroxicam

Descriptors:

  • ST4_1: Physical chemistry, chemical physics
  • ST4_2: Spectroscopic and spectrometric techniques
  • ST5_21:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Akademickie Centrum Materiałów i Nanotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Dorota Lachowicz 

Number of co-investigators in the project: 3

Call: SONATA 8 - announced on 2014-09-15

Amount awarded: 400 520 PLN

Project start date (Y-m-d): 2015-09-04

Project end date (Y-m-d): 2019-09-03

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Spektrometr UV-Vis (70 000 PLN)
  2. Spin-coater (22 500 PLN)
  3. Mieszadło magnetyczne z grzaniem (2 szt.) (7 000 PLN)
  4. Przystawka odbiciowa stanowiąca doposażenie spektrometru UV-Vis.
  5. Wyparka laboratoryjna (25 000 PLN)
  6. pH-metr, rotator laboratoryjny, termomixer do płytek hodowlanych (7 449 PLN)
  7. Wytrząsarka laboratoryjna (1 192 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (2)
  1. Coacervate Thermoresponsive Polysaccharide Nanoparticles as Delivery System for Piroxicam
    Authors:
    Dorota Lachowicz, Agnieszka Kaczynska, Anna Bodzon-Kulakowska, Anna Karewicz, Roma Wirecka, Michał Szuwarzynski, Szczepan Zapotoczny
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21(24), strony: 9664), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21249664 - link to the publication
  2. Tailoring cellular microenvironments using scaffolds based on magnetically-responsive polymer brushes
    Authors:
    Weronika Górka-Kumik, Paula Garbacz, Dorota LACHOWICZ, Paweł Dąbczyński, Szczepan Zapotoczny, Michał SZUWARZYŃSKI
    Academic press:
    Journal of Materials Chemistry. B (rok: 2020, tom: 8, strony: 10172), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/d0tb01853h - link to the publication
  3. Enhanced hyperthermic properties of biocompatible zinc ferrite nanoparticles with charged polysaccharide coating
    Authors:
    Dorota Lachowicz, Weronika Górka, Angelika Kmita, Andrzej Bernasik, Jan Żukrowski, Wojciech Szczerba, Marcin Sikora, Czesław Kapusta, Szczepan Zapotoczny
    Academic press:
    Journal of Materials Chemistry B (rok: 2019, tom: 7, strony: 2962-2973), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/C9TB00029A - link to the publication
  4. Nanohydrogels based on self-assembly of cationic pullulan and anionic dextran derivatives for efficient delivery of piroxicam
    Authors:
    Dorota Lachowicz *, Przemyslaw Mielczarek, Roma Wirecka, Katarzyna Berent, Michał Szuwarzyński, Anna Karewicz, Szczepan Zapotoczny
    Academic press:
    Pharmaceutics (rok: 2019, tom: 11(12), strony: 622), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics11120622 - link to the publication
  1. Samoorganizujące się układy polimerowe jako nośniki piroksykamu — [Self-assembled polymer systems as carriers of piroxicam]
    Authors:
    Dorota LACHOWICZ, A. Kaczyńska, A. KMITA, A. Karewicz, M. Nowakowska, S. Zapotoczny
    Conference:
    Konferencja Polskiego Towarzystwa Fizyki Medycznej (rok: 2017, ), Wydawca: Zeszyty Naukowe WCO, Letters in Oncology Science
    Data:
    konferencja 1–3 czerwca 2017
    Status:
    Published
  2. Nanohydrogels based on self-assembly of cationic curdlan and anionic hydroxypropylcellulose derivatives for piroxicam delivery
    Authors:
    D. Lachowicz, A. Kaczyńska, A. Bernasik, A. Karewicz, K. Berent, S. Zapotoczny
    Conference:
    29th Conference "Biomaterials in Medicine and Veterinary Medicine", 15-18 October 2020, Rytro, Poland (rok: 2020, ), Wydawca: Polskie Stowarzyszenie Biomateriałów/ Inżynieria Biomateriałów = Engineering of Biomaterials
    Data:
    konferencja 15-18.10.2020
    Status:
    Published