Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of intercellular interactions involving Fgf4/MAPK signalling pathway in regulation of development of mouse chimaeric embryo

2014/15/D/NZ3/02435

Keywords:

chimaera embryonic stem cells embryo blastocyst intercellular interactions

Descriptors:

  • NZ3_13: Developmental biology in animals
  • NZ3_8: Stem cell biology
  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Warszawski, Wydział Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Aneta Suwińska 

Number of co-investigators in the project: 3

Call: SONATA 8 - announced on 2014-09-15

Amount awarded: 649 400 PLN

Project start date (Y-m-d): 2015-08-10

Project end date (Y-m-d): 2019-08-09

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. oprogramowanie IMARIS Track (40 000 PLN)
  2. Dysocjator do tkanek (40 000 PLN)
  3. komputer wraz z monitorem, klawiaturą, myszką.
  4. Oprogramowanie Imaris; moduły: Core, MeasurementPro, Track.

Information in the final report

  • Publication in academic press/journals (5)
  1. FGF/ERK signaling pathway: how it operates in mammalian preimplantation embryos and embryo-derived stem cells
    Authors:
    Soszyńska A., Klimczewska K., Suwińska A.
    Academic press:
    International Journal of developmental Biology (rok: 2019, tom: 63, strony: 171-186), Wydawca: UPV/EHU Press
    Status:
    Published
    DOI:
    10.1387/ijdb.180408as - link to the publication
  2. Multi-level Fgf4- and apoptosis-dependent regulatory mechanism ensures the plasticity of ESC-chimaeric mouse embryo
    Authors:
    Soszyńska A., Filimonow K., Wigger M., Wołukanis K., Gross A., Szczepańska K. and Suwińska A.
    Academic press:
    Development (rok: 2023, tom: 150 (14), strony: dev201756), Wydawca: The Company of Biologists
    Status:
    Published
    DOI:
    10.1242/dev.201756 - link to the publication
  3. Exposure of chimaeric embryos to exogenous FGF4 leads to the production of pure ESCs-derived mice
    Authors:
    Soszyńska Anna, Krawczyk Katarzyna, Szpila Marcin, Winek Eliza, Szpakowska Anna, Suwińska Aneta
    Academic press:
    Reproduction (rok: 2023, tom: -, strony: -), Wydawca: Society for Reproduction and Fertility
    Status:
    Submitted
    DOI:
    - - link to the publication
  4. Plasticity of the inner cell mass in mouse blastocyst is restricted by the activity of Fgf/MAPK pathway
    Authors:
    Wigger M., Kisielewska K., Filimonow K., Plusa B., Maleszewski M., Suwińska A.
    Academic press:
    Scientific Reports (rok: 2017, tom: 7(1), strony: 15136), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-017-15427-0 - link to the publication
  5. The regulative nature of mammalian embryos
    Authors:
    Klimczewska K., Kasperczuk A., Suwińska A.
    Academic press:
    Current topics in developmental biology (rok: 2018, tom: 128, strony: 105-149), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10. - link to the publication

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