Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The influence of cytokine IL-6, secreted by mesenchymal stromal cells, on the formation of the new blood vessels

2014/15/B/NZ4/00696

Keywords:

Mesenchymal stromal cells angiogenesis M1 and M2 macrophages

Descriptors:

  • NZ4_12: Other related subjects
  • NZ5_7: Human disease treatment
  • NZ6_1: Adaptive and innate immunity

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Tomasz Cichoń 

Number of co-investigators in the project: 7

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 699 205 PLN

Project start date (Y-m-d): 2015-07-22

Project end date (Y-m-d): 2019-05-21

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. 0.
  2. Inkubator z kontrolą CO2 (38 000 PLN)
  3. Laminar (40 000 PLN)
  4. Zamrażarka Niskotemperaturowa.

Information in the final report

  • Publication in academic press/journals (3)
  1. Monitoring of diffusion properties and transverse relaxation time of mouse ischemic muscle after administration of human mesenchymal stromal cells derived from adipose tissue
    Authors:
    Agnieszka Skorupa, Mateusz Ciszek, Ewelina Pilny, Ryszard Smolarczyk, Magdalena Jarosz – Biej, Łukasz Boguszewicz, Łukasz Krakowczyk, Stanisław Szala, Maria Sokół, Tomasz Cichoń
    Academic press:
    Cell Proliferation (rok: 2019, tom: 52, strony: 12672), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1111/cpr.12672 - link to the publication
  2. The effect of culture media on large-scale expansion and characteristics of adipose tissue-derived mesenchymal stromal cells
    Authors:
    Czapla J, Matuszczak S, Kulik K, Wiśniewska E, Pilny E, Jaroz-Biej M, Smolarczyk R, Sirek T, Zembala M,O, Zembala M, Szala S, Cichoń T.
    Academic press:
    Stem Cell Research & Therapy (rok: 2019, tom: 10, strony: 235), Wydawca: BMC-BioMed Central The Open Access Publisher
    Status:
    Published
    DOI:
    10.1186/s13287-019-1331-9. - link to the publication
  3. Human ADSC xenograft through IL-6 secretion activates M2 macrophages responsible for the repair of damaged muscle tissue.
    Authors:
    Pilny E, Smolarczyk R, Jarosz-Biej M, Hadyk A, Skorupa A, Ciszek M, Krakowczyk Ł, Kułach N, Gillner D, Sokół M, Szala S, Cichoń T.
    Academic press:
    Stem Cell Research & Therapy (rok: 2019, tom: 10, strony: 93), Wydawca: BMC-BioMed Central The Open Access Publisher
    Status:
    Published
    DOI:
    10.1186/s13287-019-1188-y - link to the publication