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Information on the principal investigator and host institution

Information of the project and the call

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Role of stearoyl-CoA desaturase 1 (SCD1) in regulation of adipose trigliceride lipase (ATGL) and lipolysis in cardiomyocytes

2014/15/N/NZ3/04478

Keywords:

cardiomyocytes SCD1 ATGL metabolism lipolysis triglycerides

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Tomasz Bednarski 

Number of co-investigators in the project: 2

Call: PRELUDIUM 8 - announced on 2014-09-15

Amount awarded: 50 000 PLN

Project start date (Y-m-d): 2015-07-24

Project end date (Y-m-d): 2016-07-23

Project duration:: 12 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. Stearoyl-CoA desaturase 1 deficiency reduces lipid accumulation in the heart by activating lipolysis independently of peroxisome proliferator-activated receptor alpha
    Authors:
    Tomasz Bednarski, Adam Olichwier, Agnieszka Opasinska, Aleksandra Pyrkowska, Ana Maria Gan, James M. Ntambi, Pawel Dobrzyn
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (rok: 2016, tom: 1861 (12 Pt A), strony: 2029-2037), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.005 - link to the publication
  1. Lipid metabolism pathways are involved in development of obesity and hypertension related left ventricular hypertrophy
    Authors:
    Tomasz Bednarski, Monika Duda, Paweł Dobrzyń
    Conference:
    4th IRB Barcelona PhD Students Symposium: Science fights back: Tackling disease to recover homeostasis (rok: 2015, ), Wydawca: IRB Barcelona
    Data:
    konferencja 12 – 13 listopada
    Status:
    Published
  2. Development of hypertension-induced left ventricular hypertrophy is associated with impairment of lipolysis in cardiomyocytes
    Authors:
    Tomasz Bednarski, Monika Duda, Paweł Dobrzyń
    Conference:
    44th European Muscle Conference (EMC2015) (rok: 2015, ), Wydawca: Springer
    Data:
    konferencja 21 – 25 września
    Status:
    Published
  3. Stearoyl-CoA desaturase 1 regulates rate of triglyceride lipolysis in cardiomyocytes
    Authors:
    Tomasz Bednarski, Paweł Dobrzyń
    Conference:
    19th European Bioenergetics Conference (rok: 2016, ), Wydawca: Elsevier B.V.
    Data:
    konferencja 2 -7 lipca
    Status:
    Published
    DOI:
    link to the publication

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