Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Innate immune response to RSV infection, role of non-structural proteins.Experiments and modeling of signal transduction and among cells communication

2014/14/M/NZ6/00537

Keywords:

innate immunity RSV systems biology single cell experiments NF-kB IRF3 mathematical modeling stochastic processes

Descriptors:

  • NZ2_9: Systems biology
  • NZ6_1: Adaptive and innate immunity
  • NZ2_10: Biological systems analysis, modelling and simulation

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Podstawowych Problemów Techniki PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Tomasz Lipniacki 

Number of co-investigators in the project: 9

Call: HARMONIA 6 - announced on 2014-06-16

Amount awarded: 998 920 PLN

Project start date (Y-m-d): 2015-06-08

Project end date (Y-m-d): 2019-06-07

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  1. Information processing in the NF-κB pathway
    Authors:
    Tudelska K, Markiewicz J, Kochańczyk M, Czerkies M, Prus W, Korwek Z, Abdi A, Błoński S, Kaźmierczak B, Lipniacki T
    Academic press:
    Scientific Reports (rok: 2017, tom: 7, strony: 15926), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-017-16166-y - link to the publication
  2. Sampling rare events in stochastic reaction-diffusion systems within trajectory looping
    Authors:
    Żuk PJ, Kochańczyk M, Lipniacki T
    Academic press:
    Physical Review E (rok: 2018, tom: 98, strony: pp.022401-1-10), Wydawca: American Physical Society
    Status:
    Published
    DOI:
    10.1103/PhysRevE.98.022401 - link to the publication
  3. Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
    Authors:
    Czerkies M, Korwek Z, Prus W, Kochańczyk M, Jaruszewicz-Błońska J, Tudelska K, Błoński S, Kimmel M, Brasier AR, Lipniacki T.
    Academic press:
    Nature Communications (rok: 2018, tom: 9, strony: 493), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41467-017-02640-8 - link to the publication
  4. Limits to the rate of information transmission through the MAPK pathway
    Authors:
    Grabowski F, Czyż P, Kochańczyk M, Lipniacki T
    Academic press:
    Journal of the Royal Society Interface (rok: 2019, tom: 16, strony: pp.20180792-1-10), Wydawca: The Royal Society
    Status:
    Published
    DOI:
    10.1098/rsif.2018.0792 - link to the publication
  5. Traveling and standing fronts on curved surfaces
    Authors:
    Slawomir Bialecki, Pawel Nalecz-Jawecki, Bogdan Kazmierczak, Tomasz Lipniacki
    Academic press:
    Physica D: Nonlinear Phenomena (rok: 2020, tom: 401, strony: 132215-1-8), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.physd.2019.132215 - link to the publication

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