Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The association of common polymorphic variants of DNA repair genes OGG1, APE1 and PARP1 with cell growth and apoptosis

2014/13/N/NZ3/00863

Keywords:

cell biology DNA repair,polimorphisms ,cell growth apoptosis

Descriptors:

  • NZ3_1: Cell biology
  • NZ2_1: Molecular genetics

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Warszawski, Wydział Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Somayeh Shahmoradi Ghahe 

Number of co-investigators in the project: 2

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 148 716 PLN

Project start date (Y-m-d): 2015-02-04

Project end date (Y-m-d): 2019-02-03

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (4)
  1. Increased DNA repair capacity augments resistance of glioblastoma cells to photodynamic therapy
    Authors:
    Somayeh Shahmoradi Ghahe, Konrad Kosicki, Maria Wojewódzka, Bartosz A.Majchrzak, Anna Fogtman, Roksana Iwanicka-Nowicka, Agata Ciuba, Marta Koblowska, Marcin Kruszewski, Barbara Tudek, Elżbieta Speina
    Academic press:
    DNA Repair (rok: 2021, tom: 104, strony: 45307), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dnarep.2021.103136 - link to the publication
  1. The role of epigenetic mark profile, cell cycle alteration and DNA repair in resistance of glioblastoma cells to photodynamic therapy (PDT)
    Authors:
    S. Shahmoradi Ghahe, A. Ciuba, K. Kopania, M. Foksinski, R. Olinski, B. Tudek
    Conference:
    EACR-AACR-SIC SPECIAL CONFERENCE 2017 (rok: 2017, ), Wydawca: European Cancer Organisation
    Data:
    konferencja 24-27 June
    Status:
    Published
  2. The role of epigenetic mark profıle, cell cycle alteration and DNA repair in resistance of glioblastoma cells to photodynamic therapy
    Authors:
    Somayeh Shahmoradi Ghahe, Karolina Kopania, Agata Ciuba, Marek Foksinski, Ryszard Oliński, Barbara Tudek
    Conference:
    The AACR Annual Meeting 2017 (rok: 2017, ), Wydawca: Cenveo Publisher Services
    Data:
    konferencja 1-5 April
    Status:
    Published
  3. Higher capacity of DNA repair promotes resistance to the photodynamic therapy in U-87 glioblastoma cell line
    Authors:
    Somayeh Shahmoradi Ghahe, Konrad Kosicki, Marta Bak, Maria Wojewodzka, Barbara Tudek
    Conference:
    Brain Tumors 2018: From Biology to Therapy (rok: 2018, ), Wydawca: European Association for Cancer Research
    Data:
    konferencja 21-23 June
    Status:
    Published
  4. Regulatory role of DNA repair proteins APE1, OGG1 in cell proliferation and apoptosis
    Authors:
    Somayeh Shahmoradi Ghahe, Karolina Kopania, Damian Mielecki, Barbara Tudek
    Conference:
    6th EU-US Conference on Repair of Endogenous DNA Damage (rok: 2017, ), Wydawca: University of Udine
    Data:
    konferencja 24-28 September
    Status:
    Published