Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Anticancer activity of the thiosemicarbazone derivatives

2014/13/D/NZ7/00322

Keywords:

thiosemicarbazones anticancer therapy photodynamic therapy combination therapy

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ1_3: Biophysics
  • NZ3_3: Apoptosis

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Śląski w Katowicach, Wydział Matematyki, Fizyki i Chemii

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Mrozek-Wilczkiewicz 

Number of co-investigators in the project: 3

Call: SONATA 7 - announced on 2014-03-17

Amount awarded: 436 540 PLN

Project start date (Y-m-d): 2015-01-22

Project end date (Y-m-d): 2018-01-21

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. -.

Information in the final report

  • Publication in academic press/journals (9)
  • Articles in post-conference publications (2)
  1. Design, Synthesis and In Vitro Activity of Anticancer Styrylquinolines. The p53 Independent Mechanism of Action.
    Authors:
    A. Mrozek-Wilczkiewicz, E. Spaczynska, K. Malarz, W. Cieslik, M. Rams-Baron, V. Kryštof, R. Musiol
    Academic press:
    Plos One (rok: 2015, tom: 10, strony: e0142678), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0142678 - link to the publication
  2. Small molecule glycoconjugates with anticancer activity
    Authors:
    Gabriela Pastuch-Gawołek, Katarzyna Malarz, Anna Mrozek-Wilczkiewicz, Marta Musioł, Maciej Serda, Barbara Czaplinska, Robert Musiol
    Academic press:
    European Journal of Medicinal Chemistry (rok: 2016, tom: 112, strony: 130-144), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejmech.2016.01.061 - link to the publication
  3. Synthesis of new styrylquinoline cellular dyes, fluorescent properties, cellular localization and cytotoxic behavior
    Authors:
    M. Rams-Baron, M. Dulski, A. Mrozek-Wilczkiewicz, M. Korzec, W. Cieslik, E. Spaczynska, P. Bartczak, A. Ratuszna, J. Polanski, R. Musiol
    Academic press:
    Plos One (rok: 2015, tom: 10, strony: e0131210), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0131210 - link to the publication
  4. Unique properties of silver and copper silica-based nanocomposites as antimicrobial agents
    Authors:
    J. Peszke, M. Dulski, A. Nowak, K. Balin, M. Zubko, S. Sułowicz, B. Nowak, Z. Piotrowska-Seget, E. Talik, M. Wojtyniak, A. Mrozek-Wilczkiewicz, K. Malarz, and J. Szade
    Academic press:
    RSC Advances (rok: 2017, tom: 7, strony: 28092–28104), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C7RA00720E - link to the publication
  5. Comprehensive exploration of the optical and biological properties of new quinoline based cellular probes
    Authors:
    B. Czaplinska, A. Maron, J. Małecki, G. Szafraniec-Gorol, M. Matussek, K. Malarz, A. Mrozek-Wilczkiewicz, W. Danikiewicz, R. Musiol, A. Slodek
    Academic press:
    Dyes and Pigments (rok: 2017, tom: 144, strony: 119–132), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dyepig.2017.05.029 - link to the publication
  6. Pyrrolidinium-based ionic liquids as sustainable media in heat transfer processes
    Authors:
    M. Musiał, K. Malarz, A. Mrozek-Wilczkiewicz, R. Musiol, E. Zorebski, M. Dzida
    Academic press:
    ACS Sustainable Chemistry & Engineering (rok: 2017, tom: 5, strony: 11024-11033), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acssuschemeng.7b02918 - link to the publication
  7. Iron Chelators and Exogenic Photosensitizers. Synergy through Oxidative Stress Gene Expression
    Authors:
    A. Mrozek-Wilczkiewicz, K. Malarz, M. Rams-Baron, M. Serda, D. Bauer, F.-P. Montforts, A. Ratuszna, T. Burley, J. Polanski R. Musiol
    Academic press:
    Journal of Cancer (rok: 2017, tom: 8, strony: 1979–1987), Wydawca: Ivy Spring
    Status:
    Published
    DOI:
    10.7150/jca.17959 - link to the publication
  8. Piperazinyl fragment improves anticancer activity of Triapine
    Authors:
    M. Rejmund, A. Mrozek-Wilczkiewicz, K. Malarz, M. Pyrkosz-Bulska, K. Gajcy, M. Sajewicz, R. Musiol and J. Polanski
    Academic press:
    PLOS One (rok: 2018, tom: 13(4), strony: e0188767), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0188767 - link to the publication
  9. The role of oxidative stress in activity of anticancer thiosemicarbazones
    Authors:
    K. Malarz, A. Mrozek-Wilczkiewicz, M. Serda, M. Rejmund, J. Polanski, and R. Musiol
    Academic press:
    Oncotarget (rok: 2018, tom: 9(25), strony: 17689-17710), Wydawca: Impact Journals
    Status:
    Published
    DOI:
    10.18632/oncotarget.24844 - link to the publication
  1. Stable gold nanoparticles – synthesis, bioconjugation and application
    Authors:
    PAWEŁ NALEPA, ANNA MROZEK-WILCZKIEWICZ, JAROSŁAW POLAŃSKI
    Conference:
    44th Conference drug synthesis and analysis (rok: 2015, ), Wydawca: Čes. slov. Farm.
    Data:
    konferencja 2th to 4th September
    Status:
    Published
    DOI:
    link to the publication
  2. Synthesis of quinoline derivatives using a nano-Pd/Cu catalyst in the search of new fluorophores
    Authors:
    MATEUSZ KORZEC, ROKSANA RZYCKA, SANDRA SENKAŁA, EWELINA SZPACZYŃSKA, BARBARA CZAPLIŃSKA, WIOLETTA CIEŚLIK, ANNA MROZEK-WILCZKIEWICZ, MARZENA RAMS-BARON, ROBERT MUSIOŁ, JAROSŁAW POLAŃSKI
    Conference:
    44th Conference drug synthesis and analysis (rok: 2015, ), Wydawca: Čes. slov. Farm.
    Data:
    konferencja 2th to 4th September
    Status:
    Published
    DOI:
    link to the publication

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