Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Evaluation of circulating microRNA expression profiles in the pathogenesis of heart failure after acute myocardial infarction

2014/13/N/NZ5/01403

Keywords:

circulating microRNA serum microRNA expression profiles post-acute myocardial infarction heart failure pathogenesis of left ventricular remodeling

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Biochemii i Biofizyki PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Agata Maciejak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2015-02-20

Project end date (Y-m-d): 2017-02-19

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  1. miR-22-5p revealed as a potential biomarker involved in the acute phase of myocardial infarction via profiling of circulating microRNAs.
    Authors:
    Agata Maciejak, Marek Kiliszek, Grzegorz Opolski, Agnieszka Segiet, Krzysztof Matlak, Slawomir Dobrzycki, Dorota Tulacz, Grazyna Sygitowicz, Beata Burzynska, Monika Gora
    Academic press:
    Molecular Medicine Reports (rok: 2016, tom: 14, strony: 2867-75), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/mmr.2016.5566 - link to the publication
  2. Should we expect novel biomarkers of myocardial infarction?
    Authors:
    Marek Kiliszek, Agata Maciejak
    Academic press:
    Annals of Translational Medicine (rok: 2016, tom: 4, strony: 227), Wydawca: AME Publishing Company
    Status:
    Published
    DOI:
    10.21037/atm.2016.05.33 - link to the publication
  3. Circulating miR-30a-5p as a prognostic biomarker of left ventricular dysfunction after acute myocardial infarction.
    Authors:
    Maciejak A, Kostarska-Srokosz E, Gierlak W, Dluzniewski M, Kuch M, Marchel M, Opolski G, Kiliszek M, Matlak K, Dobrzycki S, Lukasik A, Segiet A, Sygitowicz G, Sitkiewicz D, Gora M, Burzynska B
    Academic press:
    Scientific Reports (rok: 2018, tom: 8, strony: 9883), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-018-28118-1 - link to the publication