Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Identification of transcripts degraded by regnase-1 and their significance in adipogenesis

2013/11/B/NZ2/00125

Keywords:

regnase-1 adpogenesis next generation sequencing proteome profile transcript degradation

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_3: Proteomics
  • NZ2_1: Molecular genetics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jolanta Jura 

Number of co-investigators in the project: 4

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 784 670 PLN

Project start date (Y-m-d): 2014-07-22

Project end date (Y-m-d): 2018-06-21

Project duration:: 47 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. ssak elektryczny.
  2. komora laminarna (39 500 PLN)
  3. komputer.
  4. zamrażarka (3 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. MCPIP1 contributes to the inflammatory response of UVB-treated keratinocytes
    Authors:
    Bugara B, Konieczny P, Wolnicka-Glubisz A, Eckhart L, Fischer H, Skalniak L, Borowczyk-Michalowska J, Drukala J, Jura J.
    Academic press:
    Journal of Dermatological Science (rok: 2017, tom: 87 (1), strony: 45583), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jdermsci.2017.03.013 - link to the publication
  2. Ectopic overexpression of MCPIP1 impairs adipogenesis by modulating microRNAs
    Authors:
    Losko M, Lichawska-Cieslar A, Kulecka M, Paziewska A, Rumienczyk I, Mikula M, Jura J.
    Academic press:
    BBA Molecular Cell Research (rok: 2018, tom: 1865 (1), strony: 186-195), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2017.09.010 - link to the publication
  3. MCPIP1, alias Regnase-1 binds and cleaves mRNA of C/EBP β
    Authors:
    Lipert B, Wilamowski M, Gorecki A, Jura J.
    Academic press:
    PLoS One (rok: 2017, tom: 12 (3), strony: 45305), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0174381 - link to the publication
  4. Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism
    Authors:
    Magdalena Losko, Dobrochna Dolicka, Natalia Pydyn, Urszula Jankowska, Sylwia Kedracka-Krok, Maria Kulecka, Agnieszka Paziewska, Michal Mikula, Piotr Major, Marek Winiarski, Andrzej Budzynski, Jolanta Jura
    Academic press:
    Cell Mol Life Sci . (rok: 2019, ), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-019-03434-5 - link to the publication
  5. MCPIP-1, Alias Regnase-1, Controls Epithelial Inflammation by Posttranscriptional Regulation of IL-8 Production
    Authors:
    Dobosz E, Wilamowski M, Lech M, Bugara B, Jura J, Potempa J, Koziel J.
    Academic press:
    Journal of Innate Immunity (rok: 2016, tom: 8 (6), strony: 564-578), Wydawca: Karger Publishers
    Status:
    Published
    DOI:
    10.1159/000448038 - link to the publication
  6. Long Noncoding RNAs in Metabolic Syndrome Related Disorders.
    Authors:
    Losko M, Kotlinowski J, Jura J.
    Academic press:
    Mediators of Inflammation (rok: 2016, tom: 2016, strony: 45303), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2016/5365209 - link to the publication

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