Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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EMMPRIN role in rat model of subarachnoid hemorrhage and in minocycline neuroprotective mechanisms.

2013/11/N/NZ7/01643

Keywords:

EMMPRIN MMP-9 subarachnoid hemorrhage blood-brain barrier,tight junctions neurodegeneration,

Descriptors:

  • NZ7_12: Prevention of human diseases
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Śląski Uniwersytet Medyczny w Katowicach, Wydział Lekarski w Katowicach

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Daria Gendosz 

Number of co-investigators in the project: 3

Call: PRELUDIUM 6 - announced on 2013-09-16

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2014-07-14

Project end date (Y-m-d): 2018-11-13

Project duration:: 52 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. The protective effect of low‐dose minocycline on brain microvascular ultrastructure in a rodent model of subarachnoid hemorrhage
    Authors:
    Daria Gendosz de Carrillo1,2 · Sebastian Student3,4 · Daniel Bula5 · Łukasz Mielańczyk2 · Małgorzata Burek6 · Patrick Meybohm6 · Halina Jędrzejowska‐Szypułka1
    Academic press:
    Histochemistry and Cell Biology (rok: 2022, ), Wydawca: Springer
    Status:
    Accepted for publication
    DOI:
    10.1007/s00418-022-02150-9 - link to the publication
  1. MINOCYCLINE PROTECTS NEUROVASCULAR UNIT FROM SUBSTANTIAL DAMAGES PRODUCED BY SUBARACHNOID HAEMORRHAGE IN RATS
    Authors:
    Daria Gendosz de Carrillo, Sebastian Student, Daniel Bula, Łukasz Mielańczyk, Halina Jędrzejowska-Szypułka
    Conference:
    XXIInd Gliwice Scientific Meetings 2018 (rok: 2018, ), Wydawca: Gliwice Scientific Meetings
    Data:
    konferencja 16-17 Listopad
    Status:
    Published
  2. Pre-Chiasmatic Subarachnoid Hemorrhage leads to disintegration of Blood-Brain Barrier, by Tight Junctions proteins disassemblance
    Authors:
    Daria Gendosz, Kamila Dębska, Halina Jędrzejowska-Szypułka, Joanna Lewin-Kowalik
    Conference:
    NEURONUS 2015 (rok: 2015, ), Wydawca: IBRO & IRUN NEUROSCIENCE FORUM
    Data:
    konferencja 17-19 Kwiecień
    Status:
    Published