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Information on the principal investigator and host institution

Information of the project and the call

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The impact of gene overexpression on selected fitness components in Saccharomyces cerevisiae

2013/11/B/NZ2/00122

Keywords:

gene expressio chronological lifespan eneuploidy mitochondria

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_3: Proteomics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Ryszard Korona 

Number of co-investigators in the project: 2

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 656 525 PLN

Project start date (Y-m-d): 2014-07-15

Project end date (Y-m-d): 2018-01-14

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  1. Gene overexpression screen for chromosome instability in yeast primarily identifies cell cycle progression genes
    Authors:
    Hanna Tutaj, Elzbieta Pogoda, Katarzyna Tomala, Ryszard Korona
    Academic press:
    Current Genetics (rok: 2019, tom: 65, strony: 483–492), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00294-018-0885-x - link to the publication
  2. Strong dominance of functional alleles over gene deletions in both intensely growing and deeply starved yeast cells
    Authors:
    Agnieszka Marek i Ryszard Korona
    Academic press:
    Journal of Evolutionary Biology (rok: 2016, tom: 29, strony: 1836-1845), Wydawca: Wiley-Blackwell
    Status:
    Published
    DOI:
    10.1111/jeb.12917 - link to the publication
  3. An Overexpression Experiment Does Not Support the Hypothesis That Avoidance of Toxicity Determines the Rate of Protein Evolution
    Authors:
    Magdalena K. Biesiadecka, Piotr Sliwa, Katarzyna Tomala, and Ryszard Korona
    Academic press:
    Genome Biology and Evolution (rok: 2020, tom: 12, strony: 589–596), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/gbe/evaa067 - link to the publication
  4. Power provides protection: Genetic robustness in yeast depends on the capacity to generate energy
    Authors:
    Marcin Plech, Katarzyna Tomala, Hanna Tutaj, Dominika Ewa Piwcewicz, J. Arjan G. M. de Visser, Ryszard Korona
    Academic press:
    PLoS Genetics (rok: 2017, tom: 2017, strony: 45308), Wydawca: PLoS
    Status:
    Published
    DOI:
    journal.pgen.1006768 - link to the publication

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