Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Evaluation of photodynamic potential of nitroimidazole-ruthenium polypyridyl complexes conjugates

2013/11/N/ST5/01606

Keywords:

ruthenium polypirydyl complexes nitroimidazol hypoxia PDT

Descriptors:

  • ST5_16:
  • ST5_14: Other related subjects

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Olga Mazuryk 

Number of co-investigators in the project: 2

Call: PRELUDIUM 6 - announced on 2013-09-16

Amount awarded: 149 980 PLN

Project start date (Y-m-d): 2014-08-19

Project end date (Y-m-d): 2017-08-18

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zbudowanie zestawu aparaturowego do naświetlania komórek w warunkach hipoksji (18 000 PLN)
  2. Dysk twardy przenośny (550 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Bioinorganic antimicrobial strategies in the resistance era
    Authors:
    Anna Regiel-Futyra, Janusz M. Dąbrowski, Olga Mazuryk, Klaudyna Śpiewak, Agnieszka Kyzioł, Barbara Pucelik, Małgorzata Brindell, Grażyna Stochel
    Academic press:
    Coordination Chemistry Reviews (rok: 2017, tom: 351, strony: 76-117), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ccr.2017.05.005 - link to the publication
  2. Engineering of relevant photodynamic processes through structural modifications of metallotetrapyrrolic photosensitizers
    Authors:
    Janusz M. Dabrowski, Barbara Pucelik, Anna Regiel-Futyra, Małgorzata Brindell, Olga Mazuryk, Agnieszka Kyzioł, Grazyna Stochel, Wojciech Macyk, Luis G. Arnaut
    Academic press:
    Coordination Chemistry Reviews (rok: 2016, tom: 325, strony: 67-101), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ccr.2016.06.007 - link to the publication
  3. New ruthenium compounds bearing semicarbazone 2-formylopyridine moiety: Playing with auxiliary ligands for tuning the mechanism of biological activity
    Authors:
    Michał Łomzik, Olga Mazuryk, Dorota Rutkowska-Zbik, Grażyna Stochel, Philippe C. Gros, Małgorzata Brindell
    Academic press:
    Journal of Inorganic Biochemistry (rok: 2017, tom: 175, strony: 80-91), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jinorgbio.2017.07.006 - link to the publication
  4. Nitroimidazole derivatives of polypyridyl ruthenium complexes: Towards understanding their anticancer activity and mode of action
    Authors:
    Olga Mazuryk, Oksana Krysiak-Foria, Agnieszka Żak, Franck Suzenet, Agata Ptak-Belowska, Tomasz Brzozowski, Grażyna Stochel, Małgorzata Brindell
    Academic press:
    European Journal of Pharmaceutical Sciences (rok: 2017, tom: 101, strony: 43-55), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejps.2017.01.020 - link to the publication

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