Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Interactions of lipopeptides with biomimetic model membranes

2013/10/E/ST4/00343

Keywords:

Lipopeptides lipids biomimetic membrane atomic force microscopy Langmuir technique electrochemistry

Descriptors:

  • ST4_5: Analytical chemistry
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Sławomir Sęk 

Number of co-investigators in the project: 9

Call: SONATA BIS 3 - announced on 2013-06-14

Amount awarded: 1 396 900 PLN

Project start date (Y-m-d): 2014-06-16

Project end date (Y-m-d): 2019-12-15

Project duration:: 66 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Dedykowane naczynko elektrochemiczne (2 szt.) (15 000 PLN)
  2. Drukarka 3D.
  3. Potencjostat (60 000 PLN)
  4. Wanna Langmuira (200 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  1. Physicochemical Characterization of Daptomycin Interaction with Negatively Charged Lipid Membranes
    Authors:
    Joanna Juhaniewicz-Dębińska, Damian Dziubak, Sławomir Sęk
    Academic press:
    Langmuir (rok: 2020, tom: 36, strony: 5324-5335), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.langmuir.0c00716 - link to the publication
  2. Effect of Interfacial Water on the Nanomechanical Properties of Negatively Charged Floating Bilayers Supported on Gold Electrodes
    Authors:
    Joanna Juhaniewicz-Dębińska, Dorota Konarzewska, Sławomir Sęk
    Academic press:
    Langmuir (rok: 2019, tom: 35, strony: 9422-9429), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.langmuir.9b01311 - link to the publication
  3. Modulation of Activity of Ultra-short Lipopeptides towards Negatively Charged Model Lipid Films
    Authors:
    Joanna Wenda, Joanna Juhaniewicz, Dagmara Tymecka, Dorota Konarzewska, Sławomir Sęk
    Academic press:
    Langmuir (rok: 2017, tom: 33, strony: 4619–4627), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.langmuir.6b04674 - link to the publication
  4. Physicochemical and Biological Characterization of Novel Membrane-Active Cationic Lipopeptides with Antimicrobial Properties
    Authors:
    Joanna Juhaniewicz-Dębińska, Robert Lasek, Dagmara Tymecka, Kinga Burdach, Dariusz Bartosik, and Sławomir Sęk
    Academic press:
    Langmuir (rok: 2020, tom: 36, strony: 12900-12910), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.langmuir.0c02135 - link to the publication
  5. Interactions of Linear Analogs of Battacin with 3 Negatively Charged Lipid Membranes
    Authors:
    Kinga Burdach, Dagmara Tymecka, Aneta Urban, Robert Lasek, Dariusz Bartosik, Slawomir Sek
    Academic press:
    Membranes (rok: 2021, tom: 11, strony: 192), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/membranes11030192 - link to the publication
  6. Characterization of Planar Biomimetic Lipid Films Composed of Phosphatidylethanolamines and Phosphatidylglycerols from Escherichia coli
    Authors:
    Dorota Konarzewska, Joanna Juhaniewicz, Alisan Guzeloglu, Sławomir Sęk
    Academic press:
    Biochimica et Biophysica Acta - Biomembranes (rok: 2017, tom: 1859, strony: 475-483), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2017.01.010 - link to the publication
  7. Diverse effect of cationic lipopeptide on negatively charged and neutral lipid bilayers supported on gold electrodes
    Authors:
    Joanna Juhaniewicz-Dębińska, Dagmara Tymecka, Sławomir Sęk
    Academic press:
    Electrochimica Acta (rok: 2019, tom: 298, strony: 735-744), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.electacta.2018.12.139 - link to the publication
  8. Lipopeptide-induced changes in permeability of solid supported bilayers composed of bacterial membrane lipids
    Authors:
    Joanna Juhaniewicz-Dębińska, Dagmara Tymecka, Sławomir Sęk
    Academic press:
    Journal of Electroanalytical Chemistry (rok: 2018, tom: 812, strony: 227-234), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jelechem.2017.12.065 - link to the publication