Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Cell replacement therapy for restoring motor function in paraplegic rats - selective activation of serotonergic neurons grafted intraspinally.

2013/09/B/NZ4/02885

Keywords:

paraplegic rats spinal cord injury transplantation serotonergic neurons locomotor recovery transgenic rats DREADD

Descriptors:

  • NZ4_7: Neurophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Urszula Sławińska 

Number of co-investigators in the project: 7

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 1 128 800 PLN

Project start date (Y-m-d): 2014-03-11

Project end date (Y-m-d): 2018-03-10

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Mikroskop fluorescencyjny z systemem komputerowym do wykonania mikrofotografii (200 000 PLN)
  2. Stereoskopowy fluorescencyjny mikroskop dysekcyjny (150 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Cholinergic Mechanisms in Spinal Locomotion - Potential Target for Rehabilitation Approaches
    Authors:
    Jordan LM , McVagh JR, Noga BR, Cabaj AM, Majczyński H, Sławińska U, Provencher J, Leblond H, Rossignol S.
    Academic press:
    Frontiers in Neural Circuits (rok: 2014, tom: 8, strony: 132), Wydawca: frontiers
    Status:
    Published
    DOI:
    10.3389/fncir.2014.00132. - link to the publication
  2. Intraspinal Grafting of Serotonergic Neurons Modifies Expression of Genes Important for Functional Recovery in Paraplegic Rats
    Authors:
    Miazga K, Fabczak H, Joachimiak E, Zawadzka M, Krzemień-Ojak Ł, Bekisz M1, Bejrowska A, Jordan LM, Sławińska U.
    Academic press:
    Neural Plasticity (rok: 2018, tom: 2018, strony: 15), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2018/4232706 - link to the publication