Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Potential influence of epigenetic drift on the age-related changes of the SIRT6 expression in human peripheral blood mononuclear cells.

2013/09/N/NZ3/01363

Keywords:

sirtuin 6 aging epigenetics miRNA methylation

Descriptors:

  • NZ3_4: Ageing

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Magdalena Owczarz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 148 140 PLN

Project start date (Y-m-d): 2014-03-25

Project end date (Y-m-d): 2017-10-24

Project duration:: 43 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  1. Age-related epigenetic drift deregulates SIRT6 expression and affects its downstream genes in human peripheral blood mononuclear cells
    Authors:
    Magdalena Owczarz, Jacek Połosak, Anna Domaszewska-Szostek, Paulina Kołodziej, Alina Kuryłowicz, Monika Puzianowska-Kuźnicka
    Academic press:
    Epigenetics (rok: 2020, tom: 15, strony: 45303), Wydawca: Taylor and Francis Group
    Status:
    Published
    DOI:
    10.1080/15592294.2020.1780081 - link to the publication