Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Tissue-engineered model of human endometrial stroma: an in vitro toxicological study

2013/09/N/NZ5/03062

Keywords:

Endometrium 3D culture bisphenol A toxicology pathology

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_9: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Rozrodu Zwierząt i Badań Żywności PAN

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Chiara Mannelli 

Number of co-investigators in the project: 3

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 99 970 PLN

Project start date (Y-m-d): 2014-04-01

Project end date (Y-m-d): 2016-03-31

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (5)
  1. Bisphenol-A modulates receptivity and secretory function of human decidual cells: an in vitro study
    Authors:
    Mannelli Ch, Szóstek AZ, Lukasik K, Carotenuto C-P, Ietta F, Romagnoli R, Ferretti C, Paulesu L, Wołczynski S, Skarzynski DJ
    Academic press:
    Reproduction (rok: 2015, tom: Aug;150(2), strony: 115-25), Wydawca: Society for Reproduction and Fertility
    Status:
    Published
    DOI:
    10.1530/REP-14-0601 - link to the publication
  2. Biological Tools to Study the Effects of Environmental Contaminants at the Feto–Maternal Interface
    Authors:
    Mannelli Ch, Ietta F, Avanzati AM, Skarzynski DJ, Paulesu L
    Academic press:
    Dose Response (rok: 2015, tom: Nov 12;13(4), strony: 1559325815611900), Wydawca: SAGE
    Status:
    Published
    DOI:
    10.1177/1559325815611902 - link to the publication
  3. Bisphenol-A alters hormone and cytokine release by humans placenta
    Authors:
    Mannelli Ch, Carotenuto C, Ietta F, Romagnoli F, Szostek AZ, Wasniewski T, Skarzynski DJ, Paulesu L.
    Academic press:
    Mediators of Inflammation (rok: 2014, tom: Art No: 635364, strony: 11), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2014/635364 - link to the publication
  1. A model of tissue – engenierd (3d) decidua to study the effects of environmental pollutions on endometrial physiology.
    Authors:
    Mannelli Ch, Szostek A, Letta F, Lukasik K, Jankowska K, Paulesu L, Skarzynski DJ
    Conference:
    SRF (rok: 2015, ), Wydawca: Society for Reproduction and Fertility
    Data:
    konferencja 20-22 lipca
    Status:
    Published
  2. Glucocorticoids trigger Macrophage Migration Inhibitory Factor (MIF) secretion by decidualized human endometrial stromal cells in vitro: the modulatory effect of Bisphenol A.
    Authors:
    Mannelli Ch, Szostek AZ, Ciaffarafà S, Carotenuto C-P, Ietta F, Romagnoli R, Piotrowska-Tomala K, Ricci Paulesu L, Skarzynski DJ.
    Conference:
    World Congress of Reproductive Biology (rok: 2014, ), Wydawca: SRF & SSR
    Data:
    konferencja September 01-04. 09. 2014
    Status:
    Published
  3. How low concentrations of Bisphenol-A can alter human implantation and pregnancy: an in vitro study on decidualized endometrial stromal cells and placenta chorionic villous explants.
    Authors:
    Mannelli Ch, Szostek AZ, Carotenuto C-P, Ietta F, Romagnoli R, Piotrowska-Tomala K, Skarzynski DJ, Paulesu L.
    Conference:
    The 1st Congress BIO'2014. Warsaw (rok: 2014, ), Wydawca: Polish Society for Cell Biology
    Data:
    konferencja 9-12 September 2014.
    Status:
    Published
  4. Environmental chemicals and reproduction: how Bisphenol A triggers a pro-inflammatory response in endometrial stromal cells
    Authors:
    Mannelli Ch, Szostek A, Carotenuto C-P, Ietta F, Romagnoli R, Piotrowska-Tomala K, Paulesu L, Skarzynski DJ.
    Conference:
    Annual Conference of Society Reproduction & Fertility (rok: 2014, ), Wydawca: SRF
    Data:
    konferencja September 2-4, 2014
    Status:
    Published
  5. In Vitro Models to Study Effects of the Environmental Chemical Bisphenol A (BPA) on the Human Feto-Maternal Interface
    Authors:
    Skarzynski DJ, Mannelli Ch, Ietta F, Bechi N, Szóstek AZ, Lukasik K, Jankowska K, Paulesu L.
    Conference:
    SSR 2016 Annual Meeting (rok: 2016, ), Wydawca: Society for the Study of Reproduction
    Data:
    konferencja July 14-21, 2016
    Status:
    Accepted for publication
    DOI:
    link to the publication

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