Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Quantitative analysis of spontaneous single-strand DNA breaks and ensuing replication stress in human cells.

2013/09/N/NZ3/00203

Keywords:

DNA damage DNA repair DNA single-strand breaks replication stress aging

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_4: Ageing

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Magdalena Kordon 

Number of co-investigators in the project: 3

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 147 410 PLN

Project start date (Y-m-d): 2014-03-20

Project end date (Y-m-d): 2017-03-19

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zewnętrzne dyski twarde USB (498 PLN)
  2. Pipety automatyczne o regulowanej objętości (2 999 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. PML-like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication-based single-strand breaks.
    Authors:
    Magdalena M. Kordon, Aleksander Szczurek, Krzysztof Berniak, Oskar Szelest, Kamil Solarczyk, Magdalena Tworzydło, Sebastian Wachsmann-Hogiu, Anne Vaahtokari, Christoph Cremer, Thoru Pederson, Jurek W. Dobrucki
    Academic press:
    The FASEB Journal (rok: 2019, tom: 33(2), strony: 2301-2313), Wydawca: The Federation of American Societies for Experimental Biology
    Status:
    Published
    DOI:
    10.1096/fj.201801379R - link to the publication
  2. Two stages of XRCC1 recruitment and two classes of XRCC1 foci formed in response to low level DNA damage induced by visible light, or stress triggered by heat shock
    Authors:
    Kamil J. Solarczyk, Magdalena Kordon, Krzysztof Berniak, Jurek W. Dobrucki
    Academic press:
    DNA Repair (rok: 2016, tom: 37, strony: 45647), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.006 - link to the publication
  1. XRCC1 recruitment to endogenous DNA damage in replicating cells - studies by quantitative confocal and super-resolution microscopy
    Authors:
    Magdalena Kordon, Aleksander Szczurek, Kirti Prakash, Hyun-Keun Lee, Udo Birk, Kamil Solarczyk, Anne Vaahtokari, Christoph Cremer, J. W. Dobrucki
    Conference:
    BIO 2014 Congress. 1st Congress of the Polish Biochemistry, Cell Biology, Biophysics and Bioinformatics (rok: 2014, ), Wydawca: Acta Biochimica Polonica
    Data:
    konferencja 9-12 wrzesień
    Status:
    Published
    DOI:
    link to the publication

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