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Information on the principal investigator and host institution

Information of the project and the call

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Nectin-3 cleavage under neuronal activation.

2013/09/N/NZ3/00108

Keywords:

nectin-3 extracellural matrix synaptic plasticity stress NMDA receptor matrix matalloprotease

Descriptors:

  • NZ3_5: Molecular neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Emilia Rejmak-Kozicka 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2014-03-11

Project end date (Y-m-d): 2017-03-10

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations
    Authors:
    van der Kooij MA*, Fantin M*, Rejmak E*, Grosse J, Zanoletti O, Fournier C, Ganguly K, Kalita K, Kaczmarek L, Sandi C * równorzędni autorzy
    Academic press:
    Nature Communications (rok: 2014, tom: 5, strony: 4995), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/ncomms5995 - link to the publication
  1. Activity-dependent cleavage of Nectin-3 is mediated by metalloproteinase
    Authors:
    Rejmak E., Kalita K., Kaczmarek L.
    Conference:
    The 1 st Congress of the Polish Biochemistry, Cell Biology, Biophysics and Bioinformatics BIO (rok: 2014, ), Wydawca: Polskie Towarzystwo Biochemiczne, Polskie Towarzystwo Biologii Komórki, Polskie Towarzystwo Biofizyki, Polskie Towarzystwo Bioinformatyki
    Data:
    konferencja 09-12.09
    Status:
    Published
  2. Regulation of nectin-3 processing in the hippocampus mediated by MMP-9 under the chronic stress conditions
    Authors:
    Rejmak E., Kalita K., Kaczmarek L.
    Conference:
    12th International Congress of the Polish Neuroscience Society (rok: 2015, ), Wydawca: Polskie Towarzystwo Badań Układu Nerwowego
    Data:
    konferencja 06-08.09
    Status:
    Published
  3. Analysis of the specificity of MMP-9 inhibitor on the nectin-3 shedding upon neuronal stimulation
    Authors:
    Rejmak E., Dziembowska M., Kalita K., Kaczmarek L.
    Conference:
    Neuroscience 2016 Society for Neuroscience (rok: 2016, ), Wydawca: Society for Neuroscience
    Data:
    konferencja 12-16.11
    Status:
    Published

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