Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The impact of P450 and UGT isoenzyme overexpression on cellular response induced by antitumor acridinone derivatives. The role of increased metabolite concentrations or the contribution of PXR and/or CAR nuclear receptors?

2013/09/B/NZ3/00003

Keywords:

drug metabolism P450 and UGT isoenzymes cellular response nuclear receptors PXR CAR enzyme induction/inhibition antitumor compounds antitumor compounds

Descriptors:

  • NZ1_2: Biochemistry
  • NZ3_1: Cell biology
  • NZ1_1: Molecular biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Politechnika Gdańska, Wydział Chemiczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Zofia Mazerska 

Number of co-investigators in the project: 7

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 843 000 PLN

Project start date (Y-m-d): 2014-03-11

Project end date (Y-m-d): 2017-03-10

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled