Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Susceptibility of human antimicrobial peptides to the action of aspartic proteases secreted by pathogenic yeast Candida albicans.

2013/09/N/NZ1/00201

Keywords:

secreted aspartic proteases Candida albicans antimicrobal peptides proteolysis LL-37 dermicidin histatin 5 defensins high molecular weight kininogen

Descriptors:

  • NZ1_2: Biochemistry
  • NZ1_10: Microbiology
  • NZ6_7: Mycology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Oliwia Bocheńska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 99 500 PLN

Project start date (Y-m-d): 2014-03-04

Project end date (Y-m-d): 2016-03-03

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. termomikser z termoblokiem (15 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (4)
  1. The action of ten secreted aspartic proteases of pathogenic yeast Candida albicans on major human salivary antimicrobial peptide, histatin 5
    Authors:
    Oliwia Bochenska, Maria Rapala-Kozik, Natalia Wolak, Wataru Aoki, Mitsuyoshi Ueda, Andrzej Kozik
    Academic press:
    Acta Biochimica Polonica (rok: 2016, tom: 63, strony: 403-410), Wydawca: Acta Biochimica Polonica
    Status:
    Published
    DOI:
    10.18388/abp.2016_1318 - link to the publication
  2. Inactivation of human kininogen-derived antimicrobial peptides by secreted aspartic proteases produced by the pathogenic yeast Candida albicans
    Authors:
    Oliwia Bocheńska, Maria Rapala-Kozik, Natalia Wolak, Wojciech Kamysz, Daria Grzywacz, Wataru Aoki, Mitsuyoshi Ueda, Andrzej Kozik
    Academic press:
    Biological Chemistry (rok: 2015, tom: 396, strony: 1369–1375), Wydawca: de Gruyter
    Status:
    Published
    DOI:
    10.1515/hsz-2015-0167 - link to the publication
  1. Inactivation of human kininogen-derived antimicrobial peptides by secrated aspartic proteases of pathogenic yeast Candida albicans
    Authors:
    O. Bochenska, M. Rapala-Kozik, N. Wolak, W. Kamysz, D. Grzywacz, W. Aoki, M. Ueda, A. Kozik
    Conference:
    42 Szkoła Zimowa Wydziału Biochemii, Biofizyki i Biotechnologii Uniwersytetu Jagiellońskiego, Zakopane, Polska (rok: 2015, ), Wydawca: Uniwersytet Jagielloński
    Data:
    konferencja 10-14 luty
    Status:
    Published
  2. Susceptibility of human antimicrobial peptides to the action of aspartic proteases secreted by pathogenic yeast Candida albicans
    Authors:
    O. Bochenska, M. Rapala-Kozik, N. Wolak, W. Aoki, M. Ueda, A. Kozik
    Conference:
    Molecules of Life. FEBS3+ Meeting, Portoroz, Słowenia (rok: 2015, ), Wydawca: Słoweńskie Towarzystwo Biochemiczne
    Data:
    konferencja 16-19 września
    Status:
    Published
  3. The action of 10 secreted aspartic proteases of pathogenic yeast Candida albicans on major human salivary peptide – histatin 5
    Authors:
    O. Bochenska, M. Rapala-Kozik, N. Wolak, W. Kamysz, D. Grzywacz, W. Aoki, M. Ueda, A. Kozik
    Conference:
    43 Szkoła Zimowa Wydziału Biochemii, Biofizyki i Biotechnologii Uniwersytetu Jagiellońskiego, Zakopane, Polska (rok: 2016, ), Wydawca: Uniwersytet Jagielloński
    Data:
    konferencja 16-20 luty
    Status:
    Published
  4. Contribution of secreted aspartic proteases of pathogenic yeast Candida albicans to the neutralization of antimicrobial function of human high molecular weight kininogen
    Authors:
    Oliwia Bochenska, Maria Rapala-Kozik, Natalia Wolak, Wojciech Kamysz, Daria Grzywacz, Wataru Aoki, Mitsuyoshi Ueda, Andrzej Kozik
    Conference:
    The FEBS EMBO 2014 Conference, Paris, France (rok: 2014, ), Wydawca: The FEBS Journal
    Data:
    konferencja 30.08 - 4.09.2014
    Status:
    Published