Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The effect of central administration of lipopolysaccharide (LPS) on the hypothalamic-pituitary-gonadal axis (HPG) in anestrous ewes

2013/09/N/NZ9/00212

Keywords:

lipopolysaccharide (LPS) hypothalamic-pituitary-gonadal axis (HPG) central nervous system (CNS) Toll-like receptor 4 (TLR4) ewe

Descriptors:

  • NZ9_2: Animal production

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Karolina Haziak 

Number of co-investigators in the project: 3

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 84 600 PLN

Project start date (Y-m-d): 2014-02-18

Project end date (Y-m-d): 2017-02-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. Effect of CD14/TLR4 antagonist on GnRH/LH secretion in ewe during central inflammation induced by intracerebroventricular administration of LPS
    Authors:
    Karolina Haziak, Andrzej Przemysław Herman, Karolina Wojtulewicz, Bartosz Pawlina, Kamila Paczesna, Joanna Bochenek and Dorota Tomaszewska-Zaremba
    Academic press:
    Journal of Animal Science and Biotechnology (rok: 2018, tom: 0,411111111111111, strony: 45301), Wydawca: BioMed Central Ltd., part of Springer Nature
    Status:
    Published
    DOI:
    10.1186/s40104-018-0267-8 - link to the publication
  1. Effect of central administration of bacterial endotoxin and TLR4 receptor antagonist on GnRH/LH secretion in anestrous ewes
    Authors:
    K. Haziak, A.P. Herman, K. Paczesna, K. Wojtulewicz, B. Pawlina, J. Bochenek, D. Tomaszewska-Zaremba
    Conference:
    XIV Conference of Young Researchers "Physiology and Biochemistry in Animal Nutrition" (rok: 2017, ), Wydawca: The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences
    Data:
    konferencja 14-15.IX.2017 r.
    Status:
    Published
  2. The effect of central lipopolysaccharide (LPS) administration on gene expression of pro-inflammatory cytokines (IL-1B, IL-6, TNFalfa) and their receptors in the hypothalamus of anestrous ewes
    Authors:
    K. Haziak, A.P. Herman, K. Kopycińska, K. Król, B. Pawlina, J. Bochenek, D. Tomaszewska-Zaremba
    Conference:
    XII International Conterence of Young Researchers "Physiology and Biochemistry in Animal Nutrition" (rok: 2015, ), Wydawca: The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences
    Data:
    konferencja 23-24.IX.2015
    Status:
    Published
  3. Wpływ dokomorowego podania endotoksyny bakteryjnej i antagonisty receptora TLR4 na poziom ekspresji genów GnRH i GnRH-R w wybranych strukturach podwzgórza i przedniej części przysadki mózgowej oraz poziom białka GnRH w wyniosłości przyśrodkowej u anestralnych owiec
    Authors:
    K. Haziak, A.P. Herman, K. Kopycińska, K. Król, B. Pawlina, J. Bochenek, D. Tomaszewska-Zaremba
    Conference:
    III Warsztaty Naukowe "Fizjologiczna regulacja procesów rozrodu i laktacji oraz skład i rola mleka matki" (rok: 2016, ), Wydawca: Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego Polskiej Akademii Nauk
    Data:
    konferencja 20-21.X.2016 r.
    Status:
    Published