Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Polyvalent proteinaceus biodegradable vector for intracellular delivery, adenovirus dodecahedron

2013/09/B/NZ3/02327

Keywords:

adenovirus dodekahedron vector endocytosis intracellular delivery

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biochemii i Biofizyki PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Szołajska 

Number of co-investigators in the project: 8

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 813 112 PLN

Project start date (Y-m-d): 2014-02-12

Project end date (Y-m-d): 2017-02-11

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komputer z oprogramowaniem (5 500 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (5)
  1. Leukocytes and drug-resistant cancer cells are targets for intracellular delivery by adenoviral dodecahedron
    Authors:
    Marta Jedynak, David Laurin, Patryk Dolega, Malgorzata Podsiadla-Bialoskorska, Inga Szurgot, Jadwiga Chroboczek, Ewa Szolajska
    Academic press:
    Nanomedicine: Nanotechnology, Biology, and Medicine (rok: 2018, tom: 14, strony: 1853-1865), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.nano.2018.05.001 - link to the publication
  2. Cholesterol and phosphatidylserine are engaged in adenoviral dodecahedron endocytosis
    Authors:
    Marta Jedynak, Remigiusz Worch, Małgorzata Podsiadła-Białoskórska, Jadwiga Chroboczek, Ewa Szołajska
    Academic press:
    BBA Biomembranes (rok: 2018, tom: brak, strony: brak), Wydawca: Elsevier
    Status:
    Accepted for publication
  3. Adenovirus dodecahedron, a VLP, can be purified by size exclusion chromatography instead of time-consuming sucrose density gradient centrifugation
    Authors:
    Szurgot Inga, Jedynak Marta, Podsiadla-Białoskorska Małgorzata, Piwowarski Jan, Szołajska Ewa, Chroboczek Jadwiga
    Academic press:
    Molecular Biotechnology (rok: 2015, tom: 45348, strony: Epub ahead of print), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12033-015-9850-9 - link to the publication
  4. Review Virus-like particles as drug delivery vectors
    Authors:
    Zdanowicz Michał, Chroboczek Jadwiga
    Academic press:
    Acta Biochimica Polonica (rok: 2016, tom: 63, strony: 469-73), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/abp.2016_1275 - link to the publication
  5. Virus-like particles as vaccine.
    Authors:
    Chroboczek Jadwiga, Szurgot Inga, Szolajska Ewa
    Academic press:
    Acta Biochimica Polonica (rok: 2014, tom: 61, strony: 531-539), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
  1. Evaluation of adenoviral dodecahedron in vivo tropism.
    Authors:
    JEDYNAK M., SZURGOT I., ŻOCHOWSKA M., PODSIADŁA-BIAŁOSKÓRSKA M., CHROBOCZEK J., SZOŁAJSKA E.
    Conference:
    ICONAN - International Conference of Nanomedicine and Nanobiotechnology, Barcelona, Spain (rok: 2017, ), Wydawca: Pompeu Fabra University, Barcelona
    Data:
    konferencja 25-27 September
    Status:
    Published
  2. Use of biomolecules delivery vector, adenovirus dodecahedron, for targeted cancer therapy.
    Authors:
    JEDYNAK M., SZURGOT I., ŻOCHOWSKA M., SZOŁAJSKA E., JEMIELITY J., DUFOUR J.F., CHROBOCZEK J.
    Conference:
    40th FEBS Congress: The Biochemical Basis of Life (rok: 2015, ), Wydawca: Wiley Online Library
    Data:
    konferencja 4-9 lipca
    Status:
    Published
  3. Adenovirus dodecahedron as a nanoplatform for cancer therapy.
    Authors:
    SZOŁAJSKA E., JEDYNAK M., LAURIN D., PODSIADŁA-BIAŁOSKÓRSKA M., ŻOCHOWSKA M., CHROBOCZEK J.
    Conference:
    BIT's 7th Annual International Symposium of Drug Delivery Systems, Prague, Czech Republic (rok: 2017, ), Wydawca: BIT Group Global Ltd.
    Data:
    konferencja 12-14 July
    Status:
    Published
  4. Adenovirus dodecahedron use as drug and antigen nanoplatform for cancer therapy
    Authors:
    JEDYNAK M., SZURGOT I., PODSIADŁA-BIAŁOSKÓRSKA M., CHROBOCZEK J., SZOŁAJSKA E.
    Conference:
    4th International Conference on Nanotechnology in Medicine, Warsaw, Poland (rok: 2016, ), Wydawca: Warsaw University of Life Sciences
    Data:
    konferencja 7-9 listopada
    Status:
    Published
  5. Application of Adenovirus dodecahedron delivery vector as a new approach in overcoming drug resistance.
    Authors:
    JEDYNAK M., DOLEGA P., PODSIADŁA-BIAŁOSKÓRSKA M., CHROBOCZEK J., SZOŁAJSKA E.
    Conference:
    6th Central European Congress of Life Sciences EUROBIOTECH, Kraków, Poland, 11-14 September (rok: 2017, ), Wydawca: Targi w Krakowie
    Data:
    konferencja 11-14 September
    Status:
    Published